DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naus and Filip1

DIOPT Version :9

Sequence 1:	NP_001286565.1	Gene:	Naus / 37076	FlyBaseID:	FBgn0034308	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	NP_001344281.1	Gene:	Filip1 / 70598	MGIID:	1917848	Length:	1229	Species:	Mus musculus

Alignment Length:	382	Identity:	101/382 - (26%)
Similarity:	179/382 - (46%)	Gaps:	48/382 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EQNSN--------SSVADTFAEAPATDADYGTENCSGSGMSVGDTVSANHEFQTMKPGPGVVHKV 58
            |.:||        |.::....:.|:.||.....|..|.     |.|.|:          |.|.:.
Mouse    24 ESSSNGHVSCPKPSIISSDGGKGPSEDAKKNKANRKGE-----DDVMAS----------GTVKRH 73

  Fly    59 MPVANSASSATATNGRTRSEMPHSELVKMLYYLEGELQARDVCIAALRNERVKQLIAQLRTKRLQ 123
            :..:..:...|    :...|:...:|:::|..:|||||||:..|..|:.|:.|..:.:......:
Mouse    74 LKPSGESEKKT----KKPLELSKEDLIQLLSIMEGELQAREDVIHMLKTEKTKPEVLEAHYGSAE 134

  Fly   124 PNDPYAAIFRDKIALNGNLISRESSTQAAQAEMEVRQIIEQQMEQQYQMVSKQRATHVRMVNILT 188
            |......:.||.|              .||.:.....:.|:.:.:..::..||:.|:.||:..|.
Mouse   135 PEKVLRVLHRDAI--------------LAQEKSIGEDVYEKPISELDRLEEKQKETYRRMLEQLL 185

  Fly   189 ESLENNQRMLQELEEEKRKHENTTAQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKKLQET 253
            .:.:.::|.:.|||.||.||.:...:.||.|..||.||.:||:.||:|:|..|:.||:..|....
Mouse   186 LAEKCHRRTVYELENEKHKHTDYMNKSDDFTNLLEQERERLKKLLEQEKAYQARKEKENAKRLNK 250

  Fly   254 LEYERNRQKQIVLLLIAERKKILMKYIEEGKRSEDLAQILAEEKQRSDTIAEGLEEESKKSLRME 318
            |..|..:.|...|:|:.||:..:.:...:.::.:||.|.|.||:::...|....:|:.:|.|::|
Mouse   251 LRDELVKLKSFALMLVDERQMHIEQLGLQSQKVQDLTQKLREEEEKLKAITYKSKEDRQKLLKLE 315

  Fly   319 EELEKQTHAMEQERKVLFAKLAKEE-----LRVK--ELEQELNALRSEHEALKKQQQ 368
            .:.|.:.....||.:.:.||||.:|     ||:|  .|.|.:..|...:::|:|.::
Mouse   316 VDFEHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLSQRIEELEETNKSLQKAEE 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naus	NP_001286565.1	CortBP2	78..274	CDD:286770	59/195 (30%)
Naus	NP_001286565.1	Angiomotin_C	189..381	CDD:289044	59/187 (32%)
Filip1	NP_001344281.1	CortBP2	89..270	CDD:313023	58/194 (30%)
		SMC_N	<220..753	CDD:330553	47/153 (31%)
		PLN03209	<970..1183	CDD:178748
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23166
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010