Protein Alignment Naus and CTTNBP2NL

DIOPT Version :10

• Sequence 1: NP_611299.2
• Gene: Naus / 37076
• FlyBaseID: FBgn0034308
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_061174.1
• Gene: CTTNBP2NL / 55917
• HGNCID: 25330
• Length: 639
• Species: Homo sapiens
• Alignment Length: 656
• Identity: 174/656 - (26%)
• Similarity: 278/656 - (42%)
• Gaps: 167/656 - (25%)

  Fly    83 ELVKMLYYLEGELQARDVCIAALRNERVKQLIAQLRTKRLQPNDPYAAIFRDKIALNGNLISRES 147
            ||:.:...|||||:|||:.|.||:.:.....|.: |..:...:||..|:.||...|      :|.
Human    10 ELLTLFSILEGELEARDLVIEALKAQHRDTFIEE-RYGKYNISDPLMALQRDFETL------KEK 67

  Fly   148 STQAAQA----EMEVRQIIEQQMEQQYQMVSKQRATHVRMVNILTESLENNQRMLQELEEEKRKH 208
            :....|.    .:.:.:::.:|.:...:          ||::.|..:...:::::.:||||:::|
Human    68 NDGEKQPVCTNPLSILKVVMKQCKNMQE----------RMLSQLAAAESRHRKVILDLEEERQRH 122

  Fly   209 ENTTAQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKKLQETLEYERNRQKQIVLLLIAERK 273
            ...||:|||:||.||.||.:|.|.||.|::||.|.||:.|||...||.||:|.||:..:|:.|.|
Human   123 AQDTAEGDDVTYMLEKERERLTQQLEFEKSQVKKFEKEQKKLSSQLEEERSRHKQLSSMLVLECK 187

  Fly   274 KILMKYIEEGKRSEDLAQILAEEKQRSDTIAEGLEEESKKSLRMEEELEKQTHAMEQERKVLFAK 338
            |...|..|||:::.:|:..|.:||.|...:.|.|..|.|:.|:.|.::|||....:.||:.|.||
Human   188 KATNKAAEEGQKAGELSLKLEKEKSRVSKLEEELAAERKRGLQTEAQVEKQLSEFDIEREQLRAK 252

  Fly   339 LAKEELRVKELEQELNALR-------------SEHEALKKQQQLGGSGSSVAAAKARQFSDDACA 390
            |.:||.|.|.|::|:.:|:             |.:|.|||         .|..:|       ..|
Human   253 LNREENRTKTLKEEMESLKKIVKDLEASHQHSSPNEQLKK---------PVTVSK-------GTA 301

  Fly   391 TPPMV-------------------NIAKIVQ------PTATVSSMPVSG---PQTGIARSIAPGQ 427
            |.|::                   ||||:..      .|...|....:|   |:....|.:..|.
Human   302 TEPLMLMSVFCQTESFPAERTHGSNIAKMTNTGLPGPATPAYSYAKTNGHCDPEIQTTRELTAGN 366

  Fly   428 NI------RSAGIATA----------PTG--TATAAIAPLTAVLNHTTTITTTTNNTTTS----- 469
            |:      |...:|.|          |.|  |.....:||::..:..:..:|.:::.|:|
Human   367 NVENQVPPREKSVALAQEKPVENGGCPVGIETPVPMPSPLSSSGSSLSPSSTASSSLTSSPCSSP 431

  Fly   470 --------SNSNSSG-----SIGVAATAAAVAASVETAATVTVPMVAPPSPSPAKMQPTA----- 516
                    |:::|.|     .:|:.....|.....::.|..........||....:.||.
Human   432 VLTKRLLGSSASSPGYQSSYQVGINQRFHAARHKFQSQADQDQQASGLQSPPSRDLSPTLIDNSA 496

  Fly   517 ----------------TIQRAP-----------GGKYAALAAAAALDQTTTPHPHPVPIAVP--P 552
                            |.|:.|           |..|..||..|.....|:..|.|..::.|  |
Human   497 AKQLARNTVTQVLSRFTSQQGPIKPVSPNSSPFGTDYRNLANTANPRGDTSHSPTPGKVSSPLSP 561

  Fly   553 V-------TVPPAGARGAPPPI-PTKPIVPPKREPSL--------SRLGSITGSSAIAAATAATT 601
            :       |:|.| .||.|||| |.||.:.|  .||.        |:..|:|.:..:|::.::.|
Human   562 LSPGIKSPTIPRA-ERGNPPPIPPKKPGLTP--SPSATTPLTKTHSQAASLTTAEDLASSCSSNT 623

  Fly   602 AAGTAK 607
            .....|
Human   624 VVANGK 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naus	NP_611299.2	CortBP2	78..274	CDD:462860	65/194 (34%)
		SMC_prok_B	<187..>384	CDD:274008	79/209 (38%)
		PHA03247	<496..587	CDD:223021	33/140 (24%)
CTTNBP2NL	NP_061174.1	CortBP2	5..188	CDD:462860	65/194 (34%)
		SMC_prok_B	<100..>283	CDD:274008	72/182 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	387..430		8/42 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	463..490		3/26 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..609		29/100 (29%)