Protein Alignment Naus and cttnbp2nlb

DIOPT Version :9

• Sequence 1: NP_001286565.1
• Gene: Naus / 37076
• FlyBaseID: FBgn0034308
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: XP_005167092.1
• Gene: cttnbp2nlb / 556247
• ZFINID: ZDB-GENE-040724-65
• Length: 599
• Species: Danio rerio
• Alignment Length: 607
• Identity: 146/607 - (24%)
• Similarity: 248/607 - (40%)
• Gaps: 128/607 - (21%)

  Fly    82 SELVKMLYYLEGELQARDVCIAALR-----------NERVKQLIAQLRTKRLQP-------NDPY 128
            :||:.:|..|||||:|:||.|..||           .|..:.:.||.|...:|.       :||:
Zfish    14 AELLMLLSILEGELEAQDVVIHTLRVHSPRTLWPVFTEWYRTVQAQQRNTFVQERYGQYDLSDPF 78

  Fly   129 AAIFRDKIALNGNLISRESSTQAAQAEMEVRQ---------IIEQQMEQQYQMVSKQRATHVRMV 184
            .|:.||              ::.:||:.:.||         :::..|.....|..|       ::
Zfish    79 VALLRD--------------SELSQAQDDGRQSPVCLNPLGVLKLVMAHCTNMKEK-------LL 122

  Fly   185 NILTESLENNQRMLQELEEEKRKHENTTAQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKK 249
            ..|..:...::|::.:||||||:.....|.|||||..||.||::|.|.||.||||:.::|::...
Zfish   123 KQLAAAERRHRRVIADLEEEKRRRAQDAAAGDDITDMLERERDRLLQQLESERAQLERLERERSV 187

  Fly   250 LQETLEYERNRQKQIVLLLIAERKKILMKYIEEGKRSEDLAQILAEEKQRSDTIAEGLEEESKKS 314
            |......:...|:|:...|..|.:|...:..||.:|..:|::.|.:|.:..:::...||.|..::
Zfish   188 LSSQAVEDLAEQQQLSSTLAKECQKATARAEEESQRVAELSRQLEQESRAMESLKGELESERTRA 252

  Fly   315 LRMEEELEKQTHAMEQERKVLFAKLAKEELRVKELEQELNALRSEHEALKKQQQLGGSGSSVAAA 379
            .::|...|::....:.||:.:..||.|||.|.:||.::.|:|:.|.:.:|::::.|.........
Zfish   253 QQIEARTERKLAEFDTEREQMRGKLLKEEKRYQELLEQFNSLKKELDEMKEREKAGLDNEEKLKI 317

  Fly   380 KARQFSDDACATPPMVNI---AKIVQPTATVSSMPVSGPQT---------------GIARS--IA 424
            ..:..|.   .|||:..:   .||..|.|:..... :|..|               |:|.:  :.
Zfish   318 PHKATSG---ITPPVSQVEADGKIATPKASPQHKQ-NGHHTPREPEFPAEERCKEEGLADNGVVL 378

  Fly   425 PGQNIRSAGI-ATAPTGTATAAIAPLTAVLNHTTTITTTTNNTTTSSNSNSSGSIGVAATAA--- 485
            ||   .|.|. ..:|:..|:::::.........|....:...::.:..|:...||.....||
Zfish   379 PG---GSGGFQCLSPSSPASSSLSSSPCSSPVLTKRLASLGCSSPTYPSSYQASINQRFQAARHK 440

  Fly   486 ---AVAASVETAATVTVPMVAPPSPSPAKMQPTATIQRAPGGKYAALAAAAALDQTTTPHPHPVP 547
               ...|..:...||.        .||..:.|||.....|....|...|...:.|..:...:||.
Zfish   441 FQQQAEAEQQHGGTVV--------HSPRDLSPTACTPPPPDNSTAKQIARNTVTQVLSRFTNPVS 497

  Fly   548 IAVPPVTVPPAG-------ARGAP--------------PPIPT-----KPIVPPKRE-------- 578
            ..:|.....|.|       |..:|              |.||.     .|.||.|::
Zfish   498 SKLPQSNSSPFGTDYRNLAAASSPTGKSPGILSPGIRSPIIPRAEKFHSPPVPAKKQGVNQSPNS 562

  Fly   579 --PS--LSRLGSITGSSAIAAA 596
              ||  .|....:|||..:.::
Zfish   563 PVPSSRASHFPELTGSCGLTSS 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naus	NP_001286565.1	CortBP2	78..274	CDD:286770	63/218 (29%)
		Angiomotin_C	189..381	CDD:289044	58/191 (30%)
cttnbp2nlb	XP_005167092.1	CortBP2	11..212	CDD:286770	63/218 (29%)
		Orbi_VP5	106..>254	CDD:279272	45/154 (29%)
		TPR_MLP1_2	176..301	CDD:285204	33/124 (27%)
		DUF4472	<230..301	CDD:291409	20/70 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575133
Domainoid	1	1.000	102	1.000	Domainoid score	I6811
eggNOG	1	0.900	-	-		E1_KOG1103
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	123	1.000	Inparanoid score	I4704
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006973
OrthoInspector	1	1.000	-	-		otm24617
orthoMCL	1	0.900	-	-		OOG6_109427
Panther	1	1.100	-	-	O	PTHR23166
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3610
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	12	11.820