DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Naus and fam184ab

DIOPT Version :9

Sequence 1:	NP_001286565.1	Gene:	Naus / 37076	FlyBaseID:	FBgn0034308	Length:	609	Species:	Drosophila melanogaster
Sequence 2:	XP_683302.2	Gene:	fam184ab / 555640	ZFINID:	ZDB-GENE-041014-214	Length:	1145	Species:	Danio rerio

Alignment Length:	427	Identity:	91/427 - (21%)
Similarity:	177/427 - (41%)	Gaps:	108/427 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 MKPGPGVVHKVMPVANSAS----SATATNGRTRSEMPH------------------SELVKMLYY 90
            |..|.|..|...| |.|||    ::|:|:..|.:..|.                  ::|.|::|.
Zfish     1 MATGAGWQHYYNP-AGSASTGKYNSTSTSTSTSTSFPSGLTLEYTQDLHLKMSKKIAQLTKVIYA 64

  Fly    91 LEGELQARDVCIAALR---NERVKQLIAQLRTKRLQPNDPYAAIFRDKIALNGNLISRESSTQAA 152
            |..:....:..|..|:   .|.|:|::::.|.|.:|    |.:...|::.|...:.|.|.|
Zfish    65 LNTKNDEHEAAIQTLKEAHEEEVQQILSETREKIMQ----YKSKISDEMDLKRRIQSLEES---- 121

  Fly   153 QAEMEVRQIIEQQMEQQYQMVSKQR---------ATHVRMVNILTESLENNQRMLQE-------- 200
               ||:.:.:::|...::: ..:||         |.|.:.|..::..:|..:|..:|
Zfish   122 ---MELHERMKRQALDEFE-TYRQRVEDMQLCTEAQHTQRVVSMSREVEEMRRSFEEKLRSFAQL 182

  Fly   201 ---LEEEKRKHENTTAQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKKLQETLEYERNRQK 262
               .|:|||:.......|         .|.::::.|...::|.|...||.:||.:..:.|.:...
Zfish   183 QSQFEQEKRQALEELRSG---------HRQEVQELLRSHQSQNANYSKDQEKLGQLHKAEVDSLN 238

  Fly   263 QIVLLLIAERKKILMKY--------------IEEGKRSEDLA--QILAEEKQRSDTIAEGLEEES 311
            :.|..|..::|:::.:|              :|..||::.:.  .:||.:|..::...|...:|:
Zfish   239 ERVEELKQDKKRLVEEYEAKLNKAQAFYERELEAMKRTQQMTAENLLAWKKTEAELRKEFQAQEA 303

  Fly   312 --KKSL-RMEEELEK-QTHAMEQERK--VLFAKLAKEELRVKELEQELNALRSEHEALKKQQQLG 370
              :|:| ::..||:: |..|.|...|  .|.|.|...|..:|||.::|..:..:.|.::.:|:.|
Zfish   304 ALQKTLGKLRSELQRVQDEARESREKSHKLQASLMTAENNIKELHKQLEEVTKDAEIVEIRQREG 368

  Fly   371 G-------------------SGSSVAAAKARQFSDDA 388
            .                   ..|.:.:.:|.|.:.:|
Zfish   369 ECELEASRDRVQQQATEILLKASQIGSLQATQMTHEA 405

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Naus	NP_001286565.1	CortBP2	78..274	CDD:286770	46/236 (19%)
Naus	NP_001286565.1	Angiomotin_C	189..381	CDD:289044	49/243 (20%)
fam184ab	XP_683302.2	FAM184	61..271	CDD:292293	45/230 (20%)
		Smc	239..1016	CDD:224117	35/167 (21%)
		LCD1	776..>886	CDD:286837
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000