Protein Alignment Naus and C49H3.6

DIOPT Version :9

• Sequence 1: NP_001286565.1
• Gene: Naus / 37076
• FlyBaseID: FBgn0034308
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_501316.2
• Gene: C49H3.6 / 177577
• WormBaseID: WBGene00016792
• Length: 552
• Species: Caenorhabditis elegans
• Alignment Length: 542
• Identity: 147/542 - (27%)
• Similarity: 246/542 - (45%)
• Gaps: 114/542 - (21%)

  Fly    55 VHKVMPVANSASSATATNGRTRSEMPHSELVKMLYYLEGELQARDVCIAALRNERVKQLIAQLRT 119
            :.||.|..::.......|     :....||:|:|.::|||:|||:..|..|:.||.|.|:::.:.
 Worm    25 IRKVQPEYDNLPEEQGVN-----DFSSDELMKLLSFMEGEVQAREDVIDHLKRERTKILLSEAKY 84

  Fly   120 KRLQPNDPYAAIFRDKIALNGNLISRESSTQAAQAEMEVRQIIEQQMEQQYQMVSKQRATHVRMV 184
            .:|..|||:||:.||. |:.|..|..|          ::.|:.|.|::|..:|::.|:.:. |..
 Worm    85 GKLNMNDPFAALRRDS-AITGEQIDEE----------KIVQMYESQVDQLDKMMAVQKQSQ-RNA 137

  Fly   185 NILTESLENNQ-RMLQELEEEKRKHENTTAQGDDITYGLELERNKLKQDLE---EERAQVAKMEK 245
            .:|..:||..| :::::||.::........||||:...||.|||:|:|.:|   ||:.: |::.|
 Worm   138 AVLLVALEKKQYKLVKKLEADREAKIRYAKQGDDLVAHLEKERNQLQQQIEFHIEEKRK-AEIAK 201

  Fly   246 DLKKLQETLEYERNRQKQIVLLLIAERKKILMKYIEEGKRSEDLAQILAEEKQRSDTIAEGLEEE 310
            |  |::.||..|:.|.:.|||.||.|||::|:|..|...::|   ||:.:  .::|....|
 Worm   202 D--KMEMTLGNEKKRHESIVLYLIQERKQMLLKMHELRVKAE---QIMLQ--NQNDPTKPG---- 255

  Fly   311 SKKSLRMEEELEKQTHAMEQERKVLFAKLAKEELRVKELEQELNALRSEHEALKKQQQLGGSGS- 374
             ..|...|.||                        ::||::|:..||:|.|:|.|.|::..:.:
 Worm   256 -PSSALSEREL------------------------IEELKKEVTFLRAERESLTKTQKMVKTENL 295

  Fly   375 SVAAAKARQFSD------DACATPPMVNIAKIVQPTATVSSMPVSGPQTG----IARSIAPGQN- 428
            |:......|.:|      :...|...::|.|   |...:..:|   |.||    ..|...|..|
 Worm   296 SLRETVRGQEADLQMLRRNLTLTGAKMSIDK---PGNVLPQLP---PDTGSLIMANRGAKPAVNR 354

  Fly   429 --------IRSAGIATAPTGTATAAIAPLTAVLNHTTTITTTTNNTTTSSNSN----------SS 475
                    .|....||.||..:....||..||   ||.:...:..:..:|:||          .:
 Worm   355 QQPAPPPVARLPNSATFPTEKSRLPRAPPPAV---TTPVPRMSIGSLPASSSNVPRTMSSPVKKT 416

  Fly   476 GSIGVAATAAAVAASVETAATVTVP---------MVAPPSPS----PAKMQPTATIQRAPGGKYA 527
            ..:||::||   ....::|||.|:|         .|.|.||.    .|.:|....:..:|.....
 Worm   417 PVMGVSSTA---VRRPQSAATTTMPTTSVITNTSAVMPLSPDLEQLEAAIQSMNVVTASPPAYST 478

  Fly   528 ALA-AAAALDQTTTPHPHPVPI 548
            |:| .:::|.:....:|...||
 Worm   479 AMAKRSSSLPREANNNPPGAPI 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naus	NP_001286565.1	CortBP2	78..274	CDD:286770	70/199 (35%)
		Angiomotin_C	189..381	CDD:289044	58/196 (30%)
C49H3.6	NP_501316.2	CortBP2	43..228	CDD:370636	70/199 (35%)
		zf-C4H2	173..>372	CDD:370830	65/241 (27%)
		Herpes_BLLF1	<350..536	CDD:282904	38/157 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	105	1.000	Domainoid score	I4186
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	125	1.000	Inparanoid score	I3281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto19405
orthoMCL	1	0.900	-	-		OOG6_109427
Panther	1	1.100	-	-	LDO	PTHR23166
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3610
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.990