DRSC/TRiP Functional Genomics Resources

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Protein Alignment Naus and cttnbp2

DIOPT Version :10

Sequence 1:NP_611299.2 Gene:Naus / 37076 FlyBaseID:FBgn0034308 Length:609 Species:Drosophila melanogaster
Sequence 2:XP_002935014.2 Gene:cttnbp2 / 100127854 XenbaseID:XB-GENE-985979 Length:1635 Species:Xenopus tropicalis


Alignment Length:657 Identity:157/657 - (23%)
Similarity:241/657 - (36%) Gaps:205/657 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    83 ELVKMLYYLEGELQARDVCIAALRNERVKQLIAQLRTKRLQPNDPYAAIFRDKIALNGNLISRES 147
            ||..:|..|||||:|||:.|.|||..| |::..|.|..|....||:.|:.||   ....|:.:|.
 Frog    37 ELRFLLSILEGELEARDLVIEALRARR-KEVFVQERYGRFNLGDPFLALQRD---FETGLVVKEK 97

  Fly   148 STQAAQAEMEVRQIIEQQMEQQYQMVSKQRATHVRMVNILTESLENNQRMLQELEEEKRKHENTT 212
            ....:..    ..|:|..|            :|.|.:         .:||..:|...:|:     
 Frog    98 KPICSNP----LTILEAVM------------SHCRKM---------QERMSAQLAAAERR----- 132

  Fly   213 AQGDDITYGLELERNKLKQDLEEERAQVAKMEKDLKKLQETLEYERNRQKQIVLLLIAERKKILM 277
                             ::.||.|..::..:|::.|||...||.||.:.|.:||:|:.|.|.:..
 Frog   133 -----------------QKKLESENTRLQNIEQEHKKLMLRLEEERAKNKHVVLILVKECKLLSG 180

  Fly   278 KYIEEGKRSEDLAQILAEEKQRSDTIAEGLEEE----SKKSLRMEEELEKQTHAMEQERKVLFAK 338
            |.|||.::.||:...|..||::...:.|.|..|    |:...:||::::||....:.||:.|.||
 Frog   181 KIIEESQKLEDVTSKLEAEKKKGAELEEALAAEKQLRSQMEAQMEDQIKKQISEFDTEREQLNAK 245

  Fly   339 LAKEELRVKELEQELNALRSEHEALK------KQQQL------------GGSGSSVAAAKARQFS 385
            |.:||.|.|||:.|::.::...|.||      |..|.            .|:||...:.:|....
 Frog   246 LCQEEARTKELQDEIDKMKKIIEQLKLSKDDNKANQALLRKNKDKHTIPAGAGSRSVSCQANILH 310

  Fly   386 DD------------ACATPPMVN--IA---KIVQPTATVSSMPVSGPQTGIARSIAP-----GQN 428
            .|            ..|.|.:||  :|   ||...|.:....|.|..||.:..|:..     |.|
 Frog   311 VDTNSENLKKSPLTTPARPSIVNHVVAGNTKINSCTNSAFLKPGSDKQTPLNDSLISLPSNHGVN 375

  Fly   429 IRSA--GIATAPTG-----------TATAAIAPLTAVLN--HTTTITTTTN-------------- 464
            :|:.  |.:..||.           |:.|:.:.|:..:.  |:...:||.|              
 Frog   376 VRTEENGSSQDPTSSTSLYPNNSFCTSPASPSYLSQSMQSLHSQCTSTTINSGLSPRIQAAKFKF 440

  Fly   465 ----------------------------------NTTTSSNSNSSGSIGVAATAAAVAASVETAA 495
                                              ||.|...|..:|..|........|..:||. 
 Frog   441 QANANEHDQNGNTTQPRELSPNSRENIAAKQMARNTVTQVLSRFTGPQGNTQLRPGFAHPMETG- 504

  Fly   496 TVTVPMVAPPSPSPAKMQPTATIQRAPGGKYAAL-AAAAALDQT-TTPHPHPVPIAVPP------ 552
              |.|.||..:..|:....:.::.|...|....: .....|.|| .||||.   :..||      
 Frog   505 --TYPPVAGRAGHPSLALKSTSVSRVDRGNPPPIPPKKPGLSQTPATPHPQ---LKAPPNVVGKS 564

  Fly   553 -----VTVPPAGARG------------APPPIPTKPIVPPKREPSLSRLGSITGSSAIAAATAAT 600
                 .:||...|.|            :.|.:|.||.:                ...:|:|....
 Frog   565 ESKPITSVPSCSAHGIRVLNEEGVSKSSSPQLPPKPTI----------------DIPVASAGCVI 613

  Fly   601 TAAGTAK 607
            .|.||::
 Frog   614 PAIGTSQ 620

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
NausNP_611299.2 CortBP2 78..274 CDD:462860 52/190 (27%)
SMC_prok_B <187..>384 CDD:274008 60/218 (28%)
PHA03247 <496..587 CDD:223021 24/115 (21%)
cttnbp2XP_002935014.2 CortBP2 32..177 CDD:462860 52/190 (27%)
YhaN 120..>283 CDD:443752 56/184 (30%)
Atrophin-1 <387..>600 CDD:460830 40/218 (18%)
ANKYR <694..846 CDD:440430
ANK repeat 697..726 CDD:293786
ANK repeat 729..759 CDD:293786
ANK repeat 761..792 CDD:293786
ANK repeat 793..824 CDD:293786
Ank_2 798..929 CDD:463710
ANK repeat 897..929 CDD:293786
Blue background indicates that the domain is not in the aligned region.

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