Protein Alignment CG10914 and GEP3

DIOPT Version :10

• Sequence 1: NP_611297.3
• Gene: CG10914 / 37075
• FlyBaseID: FBgn0034307
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_014848.1
• Gene: GEP3 / 854380
• SGDID: S000005731
• Length: 556
• Species: Saccharomyces cerevisiae
• Alignment Length: 571
• Identity: 116/571 - (20%)
• Similarity: 186/571 - (32%)
• Gaps: 204/571 - (35%)

  Fly   106 KVPCNGCGADLHCTNASLPGY------IPS-------------------EIFRDRTQQE------ 139
            ||.|..|...|...:.|.|||      :|.                   ::.:..||.:
Yeast    21 KVKCASCSIKLQDQDPSKPGYYTKPKSLPDSKLNPDLQDLKYLLFSQDIQLSKQATQNDPDLKTK 85

  Fly   140 ---LQTITCKRCHFLNHYNIALDVVVAPSTYVDTISRIQDKFALAIVLVDLLDFPCSIWPGMQNI 201
               |..:.||||....|:|.........||..|.::.: .:.:..:.:|..::||..:.|   |:
Yeast    86 RDLLLRVICKRCSNALHHNNYNPEEFPESTLNDILNYV-PRGSNVMHIVPFVEFPLHLDP---NV 146

  Fly   202 LGAKR---PVFLVGNKVDLLPRDSNIYLQHIKDSLQREFIKHGGGNGLNIKNVSLISAKTGYGIE 263
            |  ||   ...||..|.|.:.:|.|...:.: ....::|          :||...|.:...:.|.
Yeast   147 L--KRNDLDTTLVLTKSDQVFKDKNAVSKKV-PIFMKQF----------LKNTLRIDSNKTFAIS 198

  Fly   264 ELITQLHKTW-------AYKGDVYLVGCTNVGKSSLFNILLNSDYCRPEASDLVRKATTCPWPGT 321
            .|     |.|       .:|...||:|..|||||:|.|.||.
Yeast   199 AL-----KNWNISMFYNYFKNYTYLLGNPNVGKSTLINTLLQ----------------------- 235

  Fly   322 TLKLLRFPILRPSNDRVYQRFKRLVSERSEKAEMEKERRAVARETGSAAAAQPVAPVGRTFDRRE 386
              |.|.:.:...|..::          .|...|:.:|                      .|...:
Yeast   236 --KYLGYKVKIDSTGKI----------NSPSEEVMQE----------------------AFTNPK 266

  Fly   387 NLHDAFAMAGGSRPITTLNDRGKEYK-EARWVYDTPGVMQPDQISPLLTAEELV------KLQPA 444
            |...  ..|.|...|..|....:.|: ..:.::|.||.   ...:..|..|||:      :|:..
Yeast   267 NFFK--IQAAGVSHIPNLTRSVQAYQVGGKILFDLPGY---STSTSRLRLEELIDERWLQRLRKT 326

  Fly   445 TMIRPRAFRLRPQMSI---------LLGGLARL--------DLLE-ITSPRKHFDWLK--VFVFA 489
            .:...:..:.:...|:         .:||:..|        .::: |..|.|.|..::  :.||.
Yeast   327 DLFNRKHIKQKTYESMKGTSQGGCYTVGGIFYLVPPKGSINQIVKYIPGPSKTFKNIEKGIDVFN 391

  Fly   490 S------EHLPIM----IADTQEAESVYKRYVGSPFLGVPFASENLEARLRRWPGLQCKD-GDIV 543
            |      .| |:.    |......:|.||||...||:|      ::|..|        || |.|:
Yeast   392 SCNSSSGTH-PLSRYCGIKSVICEKSQYKRYAIPPFIG------SIEIVL--------KDIGYIL 441

  Fly   544 LASEGRNEETRLNCDITLSSAGWMGILLPGHSECRLRAWTPKAAGIYRREP 594
            |.:.||.|...|:                       ..|.|:...:..|||
Yeast   442 LRTTGRYEFKGLH-----------------------EIWIPRGIQVGIREP 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10914	NP_611297.3	GTPase_YqeH	109..596	CDD:213834	114/568 (20%)
		YqeH	145..332	CDD:206748	46/196 (23%)
GEP3	NP_014848.1	GTPase_YqeH	24..470	CDD:213834	114/568 (20%)
		YqeH	94..302	CDD:206748	59/288 (20%)