DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10914 and AT4G10620

DIOPT Version :9

Sequence 1:	NP_611297.3	Gene:	CG10914 / 37075	FlyBaseID:	FBgn0034307	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_567364.1	Gene:	AT4G10620 / 826654	AraportID:	AT4G10620	Length:	597	Species:	Arabidopsis thaliana

Alignment Length:	631	Identity:	131/631 - (20%)
Similarity:	220/631 - (34%)	Gaps:	201/631 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 TKIKPSF---------SIPETQQHLPDDWMDDY-----------EFYQGAQEGG----NKQGTPD 99
            :|:||.|         |||......|..:::.:           .||..:....    |:.|..:
plant    12 SKLKPLFALHLSSFKSSIPTKPNPSPPSYLNPHHFNNISKPPFLRFYSSSSSSNLLPLNRDGNYN 76

  Fly   100 PSLPASKVPCNGCGADLHCTNASLPGYI--PS--------------------EIF---------- 132
            .:...:...|.|||..:..:|...||:.  ||                    |..
plant    77 DTTSITISVCPGCGVHMQNSNPKHPGFFIKPSTEKQRNDLNLRDLTPISQEPEFIDSIKRGFIIE 141

  Fly   133 ---------RDRTQQELQTITCKRCHFLNHYNIALDVVV---APSTYVD-TISR----IQDKFAL 180
                     ||....:.:.:.|.|||.|.||....|..|   .|....| |:.|    ......:
plant   142 PISSSDLNPRDDEPSDSRPLVCARCHSLRHYGRVKDPTVENLLPDFDFDHTVGRRLGSASGARTV 206

  Fly   181 AIVLVDLLDFPCSIWPGMQNIL----------------GAKRPVFLVGNKVDLLPR--DSNIYLQ 227
            .:::||..||..|....:..::                |....|.:|..|:||||.  ..|.:.|
plant   207 VLMVVDASDFDGSFPKRVAKLVSRTIDENNMAWKEGKSGNVPRVVVVVTKIDLLPSSLSPNRFEQ 271

  Fly   228 HIKDSLQREFIKHGGGNGLNIKNVSLISAKTGYGIEELITQLHKTWAYKGDVYLVGCTNVGKSSL 292
            .::       ::...|....|..:..:|....:||::|:..:......:|.|:.||..|.|||:|
plant   272 WVR-------LRAREGGLSKITKLHFVSPVKNWGIKDLVEDVAAMAGKRGHVWAVGSQNAGKSTL 329

  Fly   293 FNILLNSDYCRPEASDLVRKATTCPWPGTTLKLLRFPILRPSNDRVYQRFKRLVSERSEKAEMEK 357
            .|.:      .......|...|..|.|||||.::|.
plant   330 INAV------GKVVGGKVWHLTEAPVPGTTLGIIRI----------------------------- 359

  Fly   358 ERRAVARETGSAAAAQPVAPVGRTFDRRENLHDAFAMAGGSRPITTLNDRGKEYKEARWVYDTPG 422
                           :.|.|.                                  ||: ::||||
plant   360 ---------------EGVLPF----------------------------------EAK-LFDTPG 374

  Fly   423 VMQPDQISPLLTAEELVKLQPATMIRPRAFRLRPQMSILLGGLARLDLLEITSPRKHFDWLKVFV 487
            ::.|.||:..||.||...:..:..::||.:|::...::.:|||.|||:.|.:     .|.|.|.|
plant   375 LLNPHQITTRLTREEQRLVHISKELKPRTYRIKEGYTVHIGGLMRLDIDEAS-----VDSLYVTV 434

  Fly   488 FASEHLPIMIADTQEAESVYKRYVGSPFLGVPFASENLEARLRRWPGLQCKDGDIVLASEGRNEE 552
            :||.::|:.:...:.|....:.:.|.. |..|...:.:| .|.:|...:.:       ..|.:.:
plant   435 WASPYVPLHMGKKENAYKTLEDHFGCR-LQPPIGEKRVE-ELGKWVRKEFR-------VSGTSWD 490

  Fly   553 TRLNCDITLSSAGWMGILLPGHSECRLRAWTPKAAGIYRREPALIP 598
            |. :.||.:|..||..:.|.|  :..|..||.:...::.|: :|:|
plant   491 TS-SVDIAVSGLGWFALGLKG--DAILGVWTHEGIDVFCRD-SLLP 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10914	NP_611297.3	GTPase_YqeH	109..596	CDD:213834	117/553 (21%)
CG10914	NP_611297.3	YqeH	145..332	CDD:206748	53/212 (25%)
AT4G10620	NP_567364.1	PRK13796	85..531	CDD:237511	117/555 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	55	1.000	Domainoid score	I4115
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D612803at2759
OrthoFinder	1	1.000	-	-		FOG0003459
OrthoInspector	1	1.000	-	-		otm2598
orthoMCL	1	0.900	-	-		OOG6_102331
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720