DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10914 and BPG2

DIOPT Version :9

Sequence 1:	NP_611297.3	Gene:	CG10914 / 37075	FlyBaseID:	FBgn0034307	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_191277.5	Gene:	BPG2 / 824885	AraportID:	AT3G57180	Length:	660	Species:	Arabidopsis thaliana

Alignment Length:	578	Identity:	129/578 - (22%)
Similarity:	224/578 - (38%)	Gaps:	165/578 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 DDWMDDYEFYQGAQEGGNKQGTP----DPSLPASKVPCNGCGADLHCTNASLPGYIPSE------ 130
            ||.|||.  .:.|.||.|.:...    :......|...|....| ........|.:..|
plant   155 DDEMDDE--IKNAIEGSNSESESGFEWESDEWEEKKEVNDVELDXFAPAGVGYGNVTEEKEKKKR 217

  Fly   131 --------IFRDRTQQE-LQTIT-CKRCHFLNHY----NIALDVVVAPSTYVDTIS-RI-----Q 175
                    |.|:..::: ...:| |.|||.|.:|    |.|.:.::....:...|| |:     .
plant   218 VSKTERKKIAREEAKKDNYDDVTVCARCHSLRNYGQVKNQAAENLLPDFDFDRLISTRLIKPMSN 282

  Fly   176 DKFALAIVLVDLLD----FPCSIWPGMQNIL--------GAKR--PVFLVGNKVDLLPRDSNIYL 226
            ....:.:::||.:|    ||......:..:|        |:|.  .:.||..||||||
plant   283 SSTTVVVMVVDCVDFDGSFPKRAAKSLFQVLQKAENDPKGSKNLPKLVLVATKVDLLP------- 340

  Fly   227 QHIKDSLQREFIKH--GGGNGLNIKNVSLISAKTGYGIEELITQLHKTWAYKGDVYLVGCTNVGK 289
            ..|..:....:::|  ..|....:..|.::||:...|::.|:..:.:....:|:|:::|..|.||
plant   341 TQISPARLDRWVRHRAKAGGAPKLSGVYMVSARKDIGVKNLLAYIKELAGPRGNVWVIGAQNAGK 405

  Fly   290 SSLFNILLNSDYCRPEASDLVRKATTCPWPGTTLKLLRF-PILRPSNDRVYQRFKRLVSERSEKA 353
            |:|.|.|...|..:      |.:.|..|.|||||.:|:. .||                  |.||
plant   406 STLINALSKKDGAK------VTRLTEAPVPGTTLGILKIGGIL------------------SAKA 446

  Fly   354 EMEKERRAVARETGSAAAAQPVAPVGRTFDRRENLHDAFAMAGGSRPITTLNDRGKEYKEARWVY 418
            :|                                                              |
plant   447 KM--------------------------------------------------------------Y 449

  Fly   419 DTPGVMQPDQISPLLTAEELVKLQPATMIRPRAFRLRPQMSILLGGLARLDLLEITSPRKHFDWL 483
            ||||::.|..:|..|.:||...::....::||::|::...|:.:|||.||||:..:     .:.:
plant   450 DTPGLLHPYLMSLRLNSEERKMVEIRKEVQPRSYRVKAGQSVHIGGLVRLDLVSAS-----VETI 509

  Fly   484 KVFVFASEHLPIMIADTQEAESVYKRYVG---SPFLGVPFASENLEARLRRWPGLQCKDGDIVLA 545
            .:.::||..:.:.:..|:.||.::|.:.|   .|.:|     ||..:.|..|     ::.:|.::
plant   510 YITIWASHSVSLHLGKTENAEEIFKGHSGLRLQPPIG-----ENRASELGTW-----EEKEIQVS 564

  Fly   546 SEGRNEETRLNCDITLSSAGWMGILLPGHSECRLRAWTPKAAGIYRREPALIPLADRL 603
              |.:.:.: :.||:::..||:.:.|.|  ...|..||.:...:..|||.:|..|..|
plant   565 --GNSWDVK-SIDISVAGLGWLSLGLKG--AATLALWTYQGIDVTLREPLVIDRAPYL 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10914	NP_611297.3	GTPase_YqeH	109..596	CDD:213834	116/532 (22%)
CG10914	NP_611297.3	YqeH	145..332	CDD:206748	56/213 (26%)
BPG2	NP_191277.5	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	55	1.000	Domainoid score	I4115
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D612803at2759
OrthoFinder	1	1.000	-	-		FOG0003459
OrthoInspector	1	1.000	-	-		otm2598
orthoMCL	1	0.900	-	-		OOG6_102331
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.720