Protein Alignment CG10914 and GNL3L

DIOPT Version :9

• Sequence 1: NP_611297.3
• Gene: CG10914 / 37075
• FlyBaseID: FBgn0034307
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_001171748.1
• Gene: GNL3L / 54552
• HGNCID: 25553
• Length: 582
• Species: Homo sapiens
• Alignment Length: 353
• Identity: 79/353 - (22%)
• Similarity: 136/353 - (38%)
• Gaps: 73/353 - (20%)

  Fly    82 YEFYQGAQEGGNKQGTPDPSLPASKVPCNGCGADLHCTNASLPGYIPSEI------FRDRTQQEL 140
            :.:.|.|::.|.|..:..||.|....|.:....:     |.|......|:      .|::.:|:.
Human    23 WPYPQPAKQNGKKATSKVPSAPHFVHPNDHANRE-----AELKKKWVEEMREKQQAAREQERQKR 82

  Fly   141 QTIT--CK-----------RCHFLNHYNI--ALDVVVAPSTYVDTISRIQDKFALAIVLVDLLD- 189
            :||.  |:           :...|...|:  .||.......|.....::.:...:.:.::|..|
Human    83 RTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDVILEVLDARDP 147

  Fly   190 FPCSIWPGMQNILGAK--RPVFLVGNKVDLLPRD-SNIYLQHIKDSLQREFIKHGGGNGLNIKNV 251
            ..|..:...:.:|.|:  :.:.||.||:||:|:: ...:|.::::.|.....|  ......:||:
Human   148 LGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTVAFK--ASTQHQVKNL 210

  Fly   252 ------------SLISAKTGYGIEELITQLHKTWAYKGDVY------LVGCTNVGKSSLFNILLN 298
                        ||:.:|..:|.|.|:..| ..:...|:|.      :||..|||||||.|.|..
Human   211 NRCSVPVDQASESLLKSKACFGAENLMRVL-GNYCRLGEVRTHIRVGVVGLPNVGKSSLINSLKR 274

  Fly   299 SDYCRPEASDLVRKATTCPWPGTTLKLLRFPILRPS-NDRVYQRFKRLVSERSEKAEMEKERRAV 362
            |..|...|...:.|.....:....::||..|.:.|. |..|....:..|       .::|
Human   275 SRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGPNSEVGTILRNCV-------HVQK----- 327

  Fly   363 ARETGSAAAAQPVAPVGRTFDRRENLHD 390
                    .|.||.|| .|..:|.||.:
Human   328 --------LADPVTPV-ETILQRCNLEE 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10914	NP_611297.3	GTPase_YqeH	109..596	CDD:213834	71/326 (22%)
		YqeH	145..332	CDD:206748	50/221 (23%)
GNL3L	NP_001171748.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		8/39 (21%)
		Required for nucleolar localization	9..35		3/11 (27%)
		Nucleostemin_like	136..307	CDD:206753	44/173 (25%)
		MnmE_helical	251..>405	CDD:331155	32/117 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140680
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.830