DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10914 and Gnl3

DIOPT Version :9

Sequence 1:	NP_611297.3	Gene:	CG10914 / 37075	FlyBaseID:	FBgn0034307	Length:	624	Species:	Drosophila melanogaster
Sequence 2:	NP_783170.1	Gene:	Gnl3 / 290556	RGDID:	631354	Length:	538	Species:	Rattus norvegicus

Alignment Length:	284	Identity:	62/284 - (21%)
Similarity:	89/284 - (31%)	Gaps:	104/284 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 ERYKDHEHVHYSSVLETKIKPSFSIPETQQHLPDDWMDDYEFYQGAQEGGNKQGTPDPSLPASKV 107
            |..|..:.:......|.|.|...|        |||...:.|..:.:.|...|:.......|..
  Rat    72 EELKQQQKLDRQKEQERKRKLEIS--------PDDEQSNVETQEESDEPKIKKAKSGKQNPKK-- 126

  Fly   108 PCNGCGADLHCTNASLPGYIPSEIFRDRTQQELQTITCKRCHFLNHYNIALDVVVAPSTYVDTIS 172
                    |||                   |||:.:       :...:|.|:|:.|.
  Rat   127 --------LHC-------------------QELKKV-------IEASDIVLEVLDAR-------- 149

  Fly   173 RIQDKFALAIVLVDLLDFPCSIWPGMQNIL---GAKRPVFLVGNKVDLLPRDS-NIYLQHIKDSL 233
                         |.|...|   |.::..:   |.|:.| ||.||.||:|::: ..:|.::...|
  Rat   150 -------------DPLGCRC---PQVEEAVIQSGCKKLV-LVLNKSDLVPKENLENWLTYLNKEL 197

  Fly   234 QREFIKHGGGNGLNIKN----------VSLISAKTGYGIEELITQLHKTWAYKG----------D 278
            .....|    ...|:||          |....:|...|.|.|       |...|          .
  Rat   198 PTVVFK----ASTNLKNRKKTFKIKKKVVPFQSKLCCGKEAL-------WKLLGGFQQSCGKGVQ 251

  Fly   279 VYLVGCTNVGKSSLFNILLNSDYC 302
            |.:||..||||||:.|.|.....|
  Rat   252 VGVVGFPNVGKSSIINSLKQERIC 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10914	NP_611297.3	GTPase_YqeH	109..596	CDD:213834	49/218 (22%)
CG10914	NP_611297.3	YqeH	145..332	CDD:206748	43/182 (24%)
Gnl3	NP_783170.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..125		12/60 (20%)
		Basic	2..46
		GN3L_Grn1	16..93	CDD:285863	5/20 (25%)
		RbgA	125..420	CDD:224083	49/223 (22%)
		Nucleostemin_like	140..302	CDD:206753	43/172 (25%)
		Intermediate	277..451
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	460..538
		Acidic	460..532
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166334367
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830