Protein Alignment CG10914 and noa-1

DIOPT Version :9

• Sequence 1: NP_611297.3
• Gene: CG10914 / 37075
• FlyBaseID: FBgn0034307
• Length: 624
• Species: Drosophila melanogaster
• Sequence 2: NP_001379241.1
• Gene: noa-1 / 174998
• WormBaseID: WBGene00013001
• Length: 787
• Species: Caenorhabditis elegans
• Alignment Length: 652
• Identity: 218/652 - (33%)
• Similarity: 341/652 - (52%)
• Gaps: 75/652 - (11%)

  Fly    20 SRRQNTAAEV-----GQSFRQRAWLLARERYKDHEHVHYSSVLETKIKPSFSIPETQQHL-PDDW 78
            |:.|.:.||.     |.|  .|.:.:..:.:.| |:|..||:   .:.|...:..|:::. .||.
 Worm   118 SKAQGSEAEAEGSTEGSS--DRGFYVEADVFVD-EYVAGSSL---DLDPGDRMVATREYFGGDDA 176

  Fly    79 MDDYEFY------QGAQEGGNKQ--------------GTPDPSLPASKVPCNGCGADLHCTNASL 123
            ::...|.      :|.|||..|.              ||.|..:|||...|.||||:.||.::||
 Worm   177 VEHISFQRPGQRAEGLQEGSGKDQDLSDDLSSEPGMIGTVDEEIPASSRKCTGCGANFHCKDSSL 241

  Fly   124 PGYIPSEIFRDRTQQELQTITCKRCHFLNHYNIALDVVVAPSTYVDTISRIQDK-FALAIVLVDL 187
            ||::|.||.....::.:....|||||.|..:|..|:|.|....|...:..::.: .:|.:::||:
 Worm   242 PGFVPLEILEKIDRRSVDQSLCKRCHLLQEHNFLLNVNVCDVDYTRMMGELKKQPESLVVLVVDV 306

  Fly   188 LDFPCSIWPGMQNILGAKRPVFLVGNKVDLLPRDSNI-YLQHIKDSLQREFIKHGGGNGLNIKNV 251
            .|.|.||:|.:.:::|::||:.:|||||||||.|:.. |:...|.:::|...|.|.....:|.:.
 Worm   307 TDLPGSIYPRLASVVGSRRPMIVVGNKVDLLPPDARTGYMWRFKKTVERAVEKAGLLENFHILHT 371

  Fly   252 SLISAKTGYGIEELITQLHKTW-----AYKGDVYLVGCTNVGKSSLFNILLNSDYCRPEASDLVR 311
            :|:|||||||||||||:::..:     ..:||::||||||.|||::||.||.||.|:..|.|||.
 Worm   372 ALVSAKTGYGIEELITEIYLKYTNVKLGMRGDIFLVGCTNAGKSTMFNALLQSDLCKVRAVDLVD 436

  Fly   312 KATTCPWPGTTLKLLRFPILRPSNDRVYQRFKRLVSERS-EKAEMEKERRAVARETGSAAAAQPV 375
            :|||..|||||:.||:||:::|...|:..|.:||::.|: .|.|| ..|:.:..|||....|.|.
 Worm   437 RATTSIWPGTTISLLKFPVMKPGPYRLEMRRRRLMAHRAWAKKEM-YARKLLLTETGDDRYAIPT 500

  Fly   376 APVGRTFDRRENLHDAFAM----------AGGSRPITTLNDRGKE------YKEARWVYDTPGVM 424
            |.:..|:...|......|:          |........|.:|.|.      :...:|.|||||.:
 Worm   501 ALIQNTYKASEEELQPMALRELHGEEEDEAEEDEKQRKLEERRKYSLEDPIFARGKWCYDTPGTV 565

  Fly   425 QPDQISPLLTAEELVKLQPATMIRPRAFRLRPQMSILLGGLARLDLLEITSPRKHFDWLKVFVFA 489
            ..:|...|.|.|||:.:.|..::||....::|..|:|:||:||||:.::....:    :.:..|.
 Worm   566 NDNQCLSLFTLEELLNVTPRRVLRPHTVLVKPGESLLIGGVARLDIEQVARAGQ----VLLTTFV 626

  Fly   490 SEHLPIMIADTQEAESVYKRYVGSPFLGVPFASENLEARLRRWPGLQCKDGDIVLASEGRNEETR 554
            :|.||:.:..|.|.|..|::::|:..|.||...|....|:..|||.:.::|::     ||..|.|
 Worm   627 NEQLPLNVMPTHECEDFYRKWLGTRALLVPQGQEAAGGRMTSWPGFRGENGEM-----GRRFEMR 686

  Fly   555 LN-------CDITLSSAGWMGILLPGHSECRLRAWTPKAAGIYRREPALIPLADRLVGKHIRYSL 612
            ..       |||.|||.||  :::....:..|.|:||...||..|...::|.:..|.||.:..|.
 Worm   687 GRLKDEGGCCDIVLSSIGW--VMVTSERDVTLSAFTPANKGITARIQPILPYSASLRGKRLPGSR 749

  Fly   613 AY 614
            .|
 Worm   750 FY 751

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10914	NP_611297.3	GTPase_YqeH	109..596	CDD:213834	184/517 (36%)
		YqeH	145..332	CDD:206748	86/193 (45%)
noa-1	NP_001379241.1	PRK13796	226..729	CDD:237511	183/514 (36%)
		YqeH	263..457	CDD:206748	86/193 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163481
Domainoid	1	1.000	100	1.000	Domainoid score	I4413
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10518
Inparanoid	1	1.050	339	1.000	Inparanoid score	I1400
Isobase	1	0.950	-	0	Normalized mean entropy	S5832
OMA	1	1.010	-	-		QHG49315
OrthoDB	1	1.010	-	-		D524165at33208
OrthoFinder	1	1.000	-	-		FOG0003459
OrthoInspector	1	1.000	-	-		oto17968
orthoMCL	1	0.900	-	-		OOG6_102331
Panther	1	1.100	-	-	LDO	PTHR46406
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R779
SonicParanoid	1	1.000	-	-		X4448
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890