DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment adp and AT4G38480

DIOPT Version :9

Sequence 1:	NP_001286563.1	Gene:	adp / 37073	FlyBaseID:	FBgn0000057	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_568042.1	Gene:	AT4G38480 / 830004	AraportID:	AT4G38480	Length:	471	Species:	Arabidopsis thaliana

Alignment Length:	591	Identity:	128/591 - (21%)
Similarity:	203/591 - (34%)	Gaps:	218/591 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SSRYQRQHTPLNASSLHWQRQQYGHELDEMLRRRLLASPAYVDRLEQEAVLVGHEGCVNCLEWTT 77
            :.|.:..|:.:|.    |:| :.|...:.....|..||...:.||..:..|..|:||||.:.:..
plant     6 AKRPRTDHSVVNV----WER-ELGLLPNRSFSNRFSASEDLLRRLGLDKKLDKHKGCVNTVSFNA 65

  Fly    78 DGMWLASGSDDYRVMIWDPFRKKLVHVIRTKHLGNVFSVKFLPKTNNSIVATCAADKFIYVYDIN 142
            ||..|.|||||.:|::||.....:.....:.|..|:|..||:|.:::..:.|.||||.:....|.
plant    66 DGDILLSGSDDRQVILWDWQTASVKLSFDSGHFNNIFQAKFMPFSDDRTIVTSAADKQVRYSKIL 130

  Fly   143 DPNETLFSCI-CHFSRAKRLATAQDSPHVFWSAGEDGCILQLDIREPHRCRPEEGIGVRLLNLHD 206
            :..:...|.: .|.....:||....||..|::.||||.:...|:|        ..:...|...
plant   131 ESGQVETSLLGKHQGPVHKLAVEPGSPFSFYTCGEDGAVKHFDLR--------TRVATNLFTC-- 185

  Fly   207 QLENTEAK--------CLAINPRRTEYLAVGTNDPFARVYDRRKLPSTNGNGLSACVAYYAPGQI 263
                .|||        .:|::||....|||...|.:|||||.|...|......:..:.::.||.:
plant   186 ----KEAKFNLVVYLHAIAVDPRNPGLLAVAGMDEYARVYDIRSYRSEGWYNFTQPIDHFCPGHL 246

  Fly   264 VKNISRNIVHEPRGITYLTFNGNGTELLVNIGCEHVYRFDLNHAEPPVFYDLPAFTSTLVHEEEP 328
            :.:       :..|||.|.|: :.:|||.:...|.:|.|..:....|..|  |:.|.|    ||
plant   247 IGD-------DHVGITGLAFS-DQSELLASYSDEFIYLFTPDMGLGPTPY--PSSTKT----EE- 296

  Fly   329 VKMPHRSRSLPTEIEVYKKEGNDFLENGKLVDAIDAYSAALAKYPQGEVLYLNRATALMRRGWFG 393
                   |..|   :|||:                               :.||.|
plant   297 -------RMTP---QVYKE-------------------------------HTNRET--------- 311

  Fly   394 DIYAALRDCHEALRLDPSYVKAHFRLARALLELHRPQDADQCLQALIQRFPDFANNHGVLMLNKD 458

plant   312 ----------------------------------------------------------------- 311

  Fly   459 IKENRRQSKSPEAPELQPVEVDDGFRYLRLKNAEYDLRSTARDYMQRYVGHCNVTTDIKEANYLG 523
                                                                     :|..|:.|
plant   312 ---------------------------------------------------------VKGVNFFG 319

  Fly   524 SQGEFIAAGSDDGNMYIWEGDTGKIRAVYRADSAIVNCVQPHPSICMLATSGIDHNIKIWSPCAA 588
            .:.|::.:|||.|.::||....|::.....||..:|||::.||.:.::.:||||.:||||:|
plant   320 PKCEYVVSGSDCGRIFIWRKKDGELLRAMEADRHVVNCIESHPHMPLMCSSGIDTDIKIWTP--- 381

  Fly   589 SAEERP 594
            ...|:|
plant   382 GGTEKP 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
adp	NP_001286563.1	WD40	54..>242	CDD:295369	60/196 (31%)
		WD40	59..>242	CDD:225201	58/191 (30%)
		WD40 repeat	72..108	CDD:293791	11/35 (31%)
		WD40 repeat	114..154	CDD:293791	11/40 (28%)
		WD40 repeat	158..203	CDD:293791	12/44 (27%)
		WD40 repeat	214..268	CDD:293791	17/61 (28%)
		TPR_11	341..410	CDD:290150	6/68 (9%)
		TPR repeat	342..370	CDD:276809	3/27 (11%)
		TPR repeat	375..408	CDD:276809	3/32 (9%)
		TPR_11	378..444	CDD:290150	3/65 (5%)
		TPR repeat	413..441	CDD:276809	0/27 (0%)
		TPR_6	415..445	CDD:289917	0/29 (0%)
		WD40 repeat	513..553	CDD:293791	11/39 (28%)
		WD40	<524..>584	CDD:225201	22/59 (37%)
		WD40	<526..584	CDD:295369	22/57 (39%)
AT4G38480	NP_568042.1	WD40	<1..95	CDD:225201	28/93 (30%)
		WD40	51..379	CDD:392136	112/528 (21%)
		WD40 repeat	60..96	CDD:293791	11/35 (31%)
		WD40 repeat	102..141	CDD:293791	11/38 (29%)
		WD40 repeat	147..186	CDD:293791	12/52 (23%)
		WD40 repeat	194..247	CDD:293791	16/52 (31%)
		WD40 repeat	254..304	CDD:293791	20/67 (30%)
		WD40 repeat	355..379	CDD:293791	11/23 (48%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270484at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820