DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment adp and AT4G35140

DIOPT Version :9

Sequence 1:	NP_001286563.1	Gene:	adp / 37073	FlyBaseID:	FBgn0000057	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001329237.1	Gene:	AT4G35140 / 829666	AraportID:	AT4G35140	Length:	541	Species:	Arabidopsis thaliana

Alignment Length:	607	Identity:	145/607 - (23%)
Similarity:	226/607 - (37%)	Gaps:	197/607 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 RVKYSSSRYQRQHTPLNASSLHWQRQQYGHELDEMLRRRLLASPAYVDRLEQEAVLVGHEGCVNC 72
            :.:...|.:...|.|:    :.:.|::.|.........|..||...|.|||....|..|:||||.
plant     4 KARRGRSNFNGLHHPV----VDFWRREVGGISSRNFSNRFSASENLVLRLEIYKKLEKHKGCVNT 64

  Fly    73 LEWTTDGMWLASGSDDYRVMIWDPFRKKLVHVIRTKHLGNVFSVKFLPKTNNSIVATCAADKFIY 137
            :.:..:|..|.|||||.||::||.....:.....:.|..|||..||:|.:::..:.|||||..:.
plant    65 VSFNAEGDVLISGSDDRRVVLWDWQLGNVKLSFHSGHANNVFQAKFMPFSDDRTIVTCAADGMVR 129

  Fly   138 VYDI--NDPNETLFSCICHFSRAKRLATAQDSPHVFWSAGEDGCILQLDIR-----EPHRCRPEE 195
            ...|  .|..||.|..: |..||.:|.....:||:|::.||||.:.:.|:|     |...||
plant   130 RASILEGDKVETSFLGL-HQGRAHKLCIEPGNPHIFYTCGEDGLVQRFDLRTEAPTELFTCR--- 190

  Fly   196 GIGVRLLNLHDQLENTEAKCLAINPRRTEYLAVGTNDPFARVYDRRKLPSTNGNGLSACVAYYAP 260
            .:..|..|    ::..:...:||:||.:...|||..:.:||:||.|:......||.:....::.|
plant   191 SVDPRRRN----MDAIQLNAIAIDPRNSNLFAVGGMEEYARLYDIRRFQGEGLNGFTRAADHFCP 251

  Fly   261 GQIVKNISRNIVHEPRGITYLTFNGNGTELLVNIGCEHVYRFDLNHAEPPVFYDLPAFTSTLVHE 325
            ..::.|       |..|||.|.|: ..:||||:...|.:|                .||..:...
plant   252 PHLIGN-------EDVGITGLAFS-EQSELLVSYNDEFIY----------------LFTPGMGLG 292

  Fly   326 EEPVKMPHRSRSLPTEIEVYKKEGNDFLENGKLVDAIDAYSAALAKYPQGEVLYLNRATALMRRG 390
            ..|:.....|:|     .|.|.|.:.
plant   293 SNPIPSSPISKS-----PVSKSESSS--------------------------------------- 313

  Fly   391 WFGDIYAALRDCHEALRLDPSYVKAHFRLARALLELHRPQDADQCLQALIQRFPDFANNHGVLML 455
                                                 .|:|               .|.|.|.::
plant   314 -------------------------------------SPKD---------------ENEHSVSLV 326

  Fly   456 NKDIKENRRQSKSPEAPELQPVEVDDGFRYLRLKNAEYDLRSTARDYMQRYVGHCNVTTDIKEAN 520
                                                              |.||.|..| :|..|
plant   327 --------------------------------------------------YKGHKNCET-VKGVN 340

  Fly   521 YLGSQGEFIAAGSDDGNMYIWEGDTGKIRAVYRADSAIVNCVQPHPSICMLATSGIDHNIKIWSP 585
            :.|.:.|::.:|||.|.::||....|::..|..||..:|||::|||.|.:||:|||:.:||:|:
plant   341 FFGPRSEYVVSGSDCGRIFIWRKKGGELIRVMEADRHVVNCIEPHPHIPVLASSGIESDIKVWT- 404

  Fly   586 CAASAEERPNLVADV----TRF 603
              :.|.||..|..::    :||
plant   405 --SKAAERATLPENIELLPSRF 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
adp	NP_001286563.1	WD40	54..>242	CDD:295369	67/194 (35%)
		WD40	59..>242	CDD:225201	63/189 (33%)
		WD40 repeat	72..108	CDD:293791	11/35 (31%)
		WD40 repeat	114..154	CDD:293791	14/41 (34%)
		WD40 repeat	158..203	CDD:293791	15/49 (31%)
		WD40 repeat	214..268	CDD:293791	16/53 (30%)
		TPR_11	341..410	CDD:290150	3/68 (4%)
		TPR repeat	342..370	CDD:276809	3/27 (11%)
		TPR repeat	375..408	CDD:276809	0/32 (0%)
		TPR_11	378..444	CDD:290150	2/65 (3%)
		TPR repeat	413..441	CDD:276809	2/27 (7%)
		TPR_6	415..445	CDD:289917	2/29 (7%)
		WD40 repeat	513..553	CDD:293791	13/39 (33%)
		WD40	<524..>584	CDD:225201	25/59 (42%)
		WD40	<526..584	CDD:295369	25/57 (44%)
AT4G35140	NP_001329237.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270484at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820