DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment adp and AT3G45620

DIOPT Version :9

Sequence 1:	NP_001286563.1	Gene:	adp / 37073	FlyBaseID:	FBgn0000057	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001190014.1	Gene:	AT3G45620 / 823704	AraportID:	AT3G45620	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	608	Identity:	143/608 - (23%)
Similarity:	216/608 - (35%)	Gaps:	243/608 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 MLRR-----RLLASPAYVDRLEQEAVLVGHEGCVNCLEWTTDGMWLASGSDDYRVMIWD--PFRK 99
            |||:     ||::  ..|.:|:....|.|||||||.:|:.:.|..|.|||||.::|:|:  ...:
plant    61 MLRKSEPIQRLIS--GRVKKLDLYGKLNGHEGCVNAVEFNSTGDVLVSGSDDRQIMLWNWLSGSR 123

  Fly   100 KLVHVIRTKHLGNVFSVKFLPKTNNSIVATCAADKFIYVYDI--NDPNETLFSCICHFSRAKRLA 162
            ||.:  .:.|..|||..||:|.|::..:.|..||..:.:..|  |...||. ....|..|..:||
plant   124 KLSY--PSGHCENVFQTKFIPFTDDRTIITSGADGQVRLGQILENGKVETK-RLGRHHGRVYKLA 185

  Fly   163 TAQDSPHVFWSAGEDGCILQLDIRE------------PHRCRPEEGIGVRLLNLHDQLENTEAKC 215
            .....|:||:|.||||.:...|||.            ...||           .|..........
plant   186 VLPGDPNVFYSCGEDGFVQHFDIRSNSATMVLYSSPFTQGCR-----------RHHSSSRIRLNS 239

  Fly   216 LAINPRRTEYLAVGTNDPFARVYDRRK----------LPSTNGNGLSACVAYYAPGQIVKNISRN 270
            :||:||.:.|||||.:|.:|||||.|:          ||       .|.|..:.|..:.:.   |
plant   240 IAIDPRNSYYLAVGGSDEYARVYDTRRVQLAPVCRHVLP-------DAPVNTFCPRHLRET---N 294

  Fly   271 IVHEPRGITYLTFNGNGTELLVNIGCEHVYRFDLNHAEPPVFYDLPAFTSTLVHEEEPVKMPHRS 335
            .||    ||.|.::..| ||||:...|.:|.|:.|                :.:...||
plant   295 SVH----ITGLAYSKAG-ELLVSYNDELIYLFEKN----------------MGYGSSPV------ 332

  Fly   336 RSLPTEIEVYKKEGNDFLENGKLVDAIDAYSAALAKYPQGEVLYLNRATALMRRGWFGDIYAALR 400

plant   333 ----------------------------------------------------------------- 332

  Fly   401 DCHEALRLDPSYVKAHFRLARALLELHRPQDADQCLQALIQRFPDFANNHGVLMLNKDIKENRRQ 465

plant   333 ----------------------------------------------------------------- 332

  Fly   466 SKSPEAPELQPVEVDDGFRYLRLKNAEYDLRSTARDYMQRYVGHCNVTTDIKEANYLGSQGEFIA 530
            |.|||  :||.:|..                       |.|:||.|..| :|..|:.|...|::.
plant   333 SVSPE--KLQEMEEP-----------------------QVYIGHRNAQT-VKGVNFFGPNDEYVT 371

  Fly   531 AGSDDGNMYIWEGDTGKIRAVYRADSAIVNCVQPHPSICMLATSGIDHNIKIWSPCA---ASAEE 592
            :|||.|:::||:...||:......|..:||.::.||.|.:||:.||:.::|:|:|.:   .|..|
plant   372 SGSDCGHIFIWKKKGGKLVRAMVGDRRVVNQLESHPHIPLLASCGIEKSVKLWTPMSNDVLSLPE 436

  Fly   593 RPNLVADVTRFVEDNQEKMRLDP 615
            :.:.|.::.|...::|.::.|.|
plant   437 KIDKVMELNRVGREDQSRVTLTP 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
adp	NP_001286563.1	WD40	54..>242	CDD:295369	70/203 (34%)
		WD40	59..>242	CDD:225201	68/198 (34%)
		WD40 repeat	72..108	CDD:293791	12/37 (32%)
		WD40 repeat	114..154	CDD:293791	12/41 (29%)
		WD40 repeat	158..203	CDD:293791	15/56 (27%)
		WD40 repeat	214..268	CDD:293791	21/63 (33%)
		TPR_11	341..410	CDD:290150	0/68 (0%)
		TPR repeat	342..370	CDD:276809	0/27 (0%)
		TPR repeat	375..408	CDD:276809	0/32 (0%)
		TPR_11	378..444	CDD:290150	0/65 (0%)
		TPR repeat	413..441	CDD:276809	0/27 (0%)
		TPR_6	415..445	CDD:289917	0/29 (0%)
		WD40 repeat	513..553	CDD:293791	13/39 (33%)
		WD40	<524..>584	CDD:225201	20/59 (34%)
		WD40	<526..584	CDD:295369	20/57 (35%)
AT3G45620	NP_001190014.1	WD40	81..424	CDD:295369	127/549 (23%)
		WD40	<81..424	CDD:225201	127/549 (23%)
		WD40 repeat	94..130	CDD:293791	12/37 (32%)
		WD40 repeat	136..176	CDD:293791	12/40 (30%)
		WD40 repeat	181..228	CDD:293791	15/57 (26%)
		WD40 repeat	238..291	CDD:293791	21/59 (36%)
		WD40 repeat	298..349	CDD:293791	22/228 (10%)
		WD40 repeat	400..424	CDD:293791	10/23 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1334
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1270484at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820