Protein Alignment adp and dcaf8

DIOPT Version :10

• Sequence 1: NP_611296.2
• Gene: adp / 37073
• FlyBaseID: FBgn0000057
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_021326944.1
• Gene: dcaf8 / 100007924
• ZFINID: ZDB-GENE-070912-578
• Length: 607
• Species: Danio rerio
• Alignment Length: 587
• Identity: 133/587 - (22%)
• Similarity: 211/587 - (35%)
• Gaps: 227/587 - (38%)

  Fly    33 QQYGHELDEMLRRRLLASPAYVDRLEQEAVLVGHEGCVNCLEWTTDGMWLASGSDDYRVMIWDPF 97
            ::.|.:..:.: |::..:...|.|||.:..|..|.||||.|.:...|..|||||||.||:|||..
Zfish   172 REIGRDSQQFV-RKVCGARGLVQRLELQGRLERHTGCVNTLHFNPSGTRLASGSDDLRVVIWDWA 235

  Fly    98 RKKLVHVIRTKHLGNVFSVKFLPKTNNSIVATCAADKFIYVYDINDPNETLFSCIC--------H 154
            |:|......:.|..|||..||||.:.:|.:|.||.|..|.|.:::....      |        |
Zfish   236 RRKAELEFDSGHKSNVFQAKFLPHSGDSTLAMCARDGQIRVAELSATQR------CKNTKRVAQH 294

  Fly   155 FSRAKRLATAQDSPHVFWSAGEDGCILQLDIREPHRCRPEEGIGVRLLNLHDQLENTEAKCLAIN 219
            ...|.:||...|||..|.|||||..:..:|:|..   ||..    :|:.:.:..:......:.:|
Zfish   295 KGAAHKLALEPDSPCSFLSAGEDAVVFGIDLRLD---RPAN----KLVVVKEGEKKVGLYTIYVN 352

  Fly   220 PRRTEYLAVGTNDPFARVYDRRKLPSTNGNGLSACVAYYAPGQIVKNISRNIVHEPRGITYLTFN 284
            |..|.:.|||..|.:.|:||:||:...:.||:   :..:.|..:|.:.|:.      .||.|.::
Zfish   353 PANTHHFAVGGRDQYVRIYDQRKINEHDNNGV---LKKFCPSHLVSSESKT------NITCLVYS 408

  Fly   285 GNGTELLVNIGCEHVYRFDLNHAEPPVFYDLPAFTSTLVHEEEPVKMPHRSRSLPTEIEVYKKEG 349
            .:|||||.:...|.:|.||.:|:
Zfish   409 HDGTELLASYNDEDIYLFDSSHS------------------------------------------ 431

  Fly   350 NDFLENGKLVDAIDAYSAALAKYPQGEVLYLNRATALMRRGWFGDIYAALRDCHEALRLDPSYVK 414
                                                                             
Zfish   432 ----------------------------------------------------------------- 431

  Fly   415 AHFRLARALLELHRPQDADQCLQALIQRFPDFANNHGVLMLNKDIKENRRQSKSPEAPELQPVEV 479
                                                                             
Zfish   432 ----------------------------------------------------------------- 431

  Fly   480 DDGFRYLRLKNAEYDLRSTARDYMQRYVGHCNVTTDIKEANYLGSQGEFIAAGSDDGNMYIWEGD 544
             ||                 .||.::|.||.|..| :|..|:.|...||:.:|||.|::|:|:.:
Zfish   432 -DG-----------------ADYHRKYKGHRNNAT-VKGVNFYGPCSEFVVSGSDCGHIYLWDKN 477

  Fly   545 TGKIRAVYRAD-SAIVNCVQPHPSICMLATSGIDHNIKIWSPCAASAEERPNLVADVTRFVEDNQ 608
            :.::......| ..:|||::|||.:..|||||:||::|:|:|.|    |.|..:..:...::.|:
Zfish   478 SARVVQFMEGDRGGVVNCLEPHPHLPGLATSGLDHDVKLWAPTA----ENPTTLKGLKEVMKKNK 538

  Fly   609 EK 610
            .:
Zfish   539 RE 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
adp	NP_611296.2	WD40	54..>242	CDD:475233	70/195 (36%)
		WD40 repeat	72..108	CDD:293791	16/35 (46%)
		WD40 repeat	114..154	CDD:293791	13/47 (28%)
		WD40 repeat	158..203	CDD:293791	17/44 (39%)
		WD40 repeat	214..268	CDD:293791	16/53 (30%)
		Spy	338..>461	CDD:443119	0/122 (0%)
		TPR repeat	342..370	CDD:276809	0/27 (0%)
		TPR repeat	375..408	CDD:276809	0/32 (0%)
		TPR repeat	413..441	CDD:276809	0/27 (0%)
		WD40 repeat	513..553	CDD:293791	12/39 (31%)
		WD40	<526..584	CDD:475233	23/58 (40%)
dcaf8	XP_021326944.1	WD40	201..518	CDD:475233	121/529 (23%)
		WD40 repeat	210..246	CDD:293791	16/35 (46%)
		WD40 repeat	252..293	CDD:293791	13/46 (28%)
		WD40 repeat	298..339	CDD:293791	17/47 (36%)
		WD40 repeat	347..390	CDD:293791	14/45 (31%)
		WD40 repeat	402..441	CDD:293791	17/228 (7%)
		WD40 repeat	449..486	CDD:293791	11/36 (31%)
		WD40 repeat	493..517	CDD:293791	14/23 (61%)