DRSC/TRiP Functional Genomics Resources

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Protein Alignment EMRE and MIEF1

DIOPT Version :9

Sequence 1:NP_611294.1 Gene:EMRE / 37071 FlyBaseID:FBgn0062440 Length:97 Species:Drosophila melanogaster
Sequence 2:NP_001291493.1 Gene:MIEF1 / 54471 HGNCID:25979 Length:478 Species:Homo sapiens


Alignment Length:89 Identity:26/89 - (29%)
Similarity:34/89 - (38%) Gaps:23/89 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 LALPISLA----LQRVSRRVAEHPHNLRILQRHMSSVYFRSGAIKPKPEEMPFGLLAIFCAVIPG 66
            :|.|..||    |.|:|.|.|| ...||.|.:..|..  ||..:|         :|...|...|.
Human   324 VAKPHRLAQYDNLWRLSLRPAE-TARLRALDQADSGC--RSLCLK---------ILKAICKSTPA 376

  Fly    67 LFVGATISKNVANFL-----EEND 85
            |  |...:..:.|.:     ||.|
Human   377 L--GHLTASQLTNVILHLAQEEAD 398

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EMRENP_611294.1 DDDD 22..90 CDD:401969 18/69 (26%)
MIEF1NP_001291493.1 Dimerization 49..195
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 57..77
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 96..123
Important for interaction with DNM1L 160..169
Mab-21 191..431 CDD:281298 26/89 (29%)
Important for interaction with DNM1L 234..242
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4542
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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