DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pAbp and PAB8

DIOPT Version :9

Sequence 1:	NP_476667.1	Gene:	pAbp / 37070	FlyBaseID:	FBgn0265297	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001185184.1	Gene:	PAB8 / 841399	AraportID:	AT1G49760	Length:	671	Species:	Arabidopsis thaliana

Alignment Length:	651	Identity:	293/651 - (45%)
Similarity:	390/651 - (59%)	Gaps:	78/651 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFDL 67
            |||||||...|.:|.||:.|:.||.|:|:|||||:.|||||||.|||:..|.||.|||:.:||..
plant    46 SLYVGDLDATVTDSQLFEAFTQAGQVVSVRVCRDMTTRRSLGYGYVNYATPQDASRALNELNFMA 110

  Fly    68 VRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKGY 132
            :..:.||:|:|.||||||:|||||:||||||::||:||:::||||||.|||||||.|..|.||||
plant   111 LNGRAIRVMYSVRDPSLRKSGVGNIFIKNLDKSIDHKALHETFSAFGPILSCKVAVDPSGQSKGY 175

  Fly   133 GFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDDE 197
            |||.::|:|||..:|||:||||||.|:||||.|:.:.:|:.. |||.| ||||||||.:|...||
plant   176 GFVQYDTDEAAQGAIDKLNGMLLNDKQVYVGPFVHKLQRDPS-GEKVK-FTNVYVKNLSESLSDE 238

  Fly   198 KLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQKK 262
            :|.:.|..:|..||..:|...:|||||||||.||.::.|..||.|||||.. :.|..:|.:||||
plant   239 ELNKVFGEFGVTTSCVIMRDGEGKSKGFGFVNFENSDDAARAVDALNGKTF-DDKEWFVGKAQKK 302

  Fly   263 AERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRSK 327
            :||:.|||:|||:..::..:...|.||||||||:::.||:||..|:|:|.|||.|||.|..|.|:
plant   303 SERETELKQKFEQSLKEAADKSQGSNLYVKNLDESVTDDKLREHFAPFGTITSCKVMRDPSGVSR 367

  Fly   328 GFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQY-------MRHMTGMRM 385
            |.|||.|:...|||.|:||:||:::.:||||||||||||:|||.|.:|:       |....|.||
plant   368 GSGFVAFSTPEEATRAITEMNGKMIVTKPLYVALAQRKEDRKARLQAQFSQMRPVNMPPAVGPRM 432

  Fly   386 QQLGQIYQPNAASGFFVPTLPSNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGFQ 450
                |:|.|...        |..|:.|..|      ..|..:||  |....|.........||
plant   433 ----QMYPPGGP--------PMGQQLFYGQ------GPPAMIPQ--PGFGYQQQLVPGMRPGG-- 475

  Fly   451 GTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITGQQTAAPNMQIPGAQIAGG 515
               ..:|..|.......:..|.|.|         ...|..|     |::.|.|..|.|...:...
plant   476 ---SPMPNFFMPMMQQGQQQQQQQQ---------QQQRPGG-----GRRGALPQPQQPSPMMQQQ 523

  Fly   516 AQQRTSNYKY-----------TSNMRNPPVP-----QLHQ-----TQPIPQQLQGKNSEKLIASL 559
            ...|...|:|           |.||.:.|..     .:|.     :||:|        ...:|:.
plant   524 MHPRGRMYRYPQRDVNTMPGPTQNMLSVPYDVSSGGGVHHRDSPTSQPVP--------IVALATR 580

  Fly   560 LANAKPQEQKQILGERLYPMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVL 624
            ||||.|::|:.:|||.|||::|.:....|.|:||||||::.:|:||::|..|||||||.||:.||
plant   581 LANAAPEQQRTMLGENLYPLVEQLEPESAAKVTGMLLEMDQTEVLHLLESPEALKAKVTEAMDVL 645

  Fly   625 Q 625
            :
plant   646 R 646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	292/649 (45%)
PAB8	NP_001185184.1	PABP-1234	46..646	CDD:130689	292/649 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2252
eggNOG	1	0.900	-	-		E1_KOG0123
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	490	1.000	Inparanoid score	I329
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		otm2763
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840