DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pAbp and PAB1

DIOPT Version :9

Sequence 1:	NP_476667.1	Gene:	pAbp / 37070	FlyBaseID:	FBgn0265297	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_174676.2	Gene:	PAB1 / 840313	AraportID:	AT1G34140	Length:	407	Species:	Arabidopsis thaliana

Alignment Length:	399	Identity:	168/399 - (42%)
Similarity:	244/399 - (61%)	Gaps:	31/399 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 LDTMNFDLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATD 124
            ::.:|:..::.||:|||:|:||||.|.||.||||:||||.:||||.:.|.|||||.:||||||.|
plant     1 MEVLNYCKLKGKPMRIMFSERDPSNRMSGRGNVFVKNLDESIDNKQLCDMFSAFGKVLSCKVARD 65

  Fly   125 EKGNSKGYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKN 189
            ..|.|||||||.|.::.:..|:.:..||.|:..:.::|..|:.|.:     .:|:::||||||||
plant    66 ASGVSKGYGFVQFYSDLSVYTACNFHNGTLIRNQHIHVCPFVSRGQ-----WDKSRVFTNVYVKN 125

  Fly   190 FTEDFDDEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSL 254
            ..|...|..||..|..:|:|||..||...:|||:.||||.||..|||..|::.:||..:.| |.|
plant   126 LVETATDADLKRLFGEFGEITSAVVMKDGEGKSRRFGFVNFEKAEAAVTAIEKMNGVVVDE-KEL 189

  Fly   255 YVARAQKKAERQQELKRKFE------ELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNI 313
            :|.|||:|..|.::||.|||      ::|.::     |:|||||||||::|:.:|...||.:|.|
plant   190 HVGRAQRKTNRTEDLKAKFELEKIIRDMKTRK-----GMNLYVKNLDDSVDNTKLEELFSEFGTI 249

  Fly   314 TSAKVMTDEEGRSKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMR 378
            ||.|||....|.|||.|||.|:.:.||:.|:.::||::||:||:||:|||.||:.|.||.:|:..
plant   250 TSCKVMVHSNGISKGVGFVEFSTSEEASKAMLKMNGKMVGNKPIYVSLAQCKEQHKLHLQTQFNN 314

  Fly   379 HMTGMRMQQL-GQIYQPNAASGFFVPTLPSNQRFFGSQVATQMRNT------PRWV------PQV 430
            .......|.: .|:..|........|....|.:.: |...::|.|:      |.::      |.:
plant   315 PPPSPHQQPIFSQVVAPATMLSQQTPLRGYNFQPY-SMCGSRMPNSCPPISIPNFMVPQPFRPTL 378

  Fly   431 RPPAAIQGV 439
            .|||.:.|:
plant   379 YPPAPLVGL 387

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	168/399 (42%)
PAB1	NP_174676.2	RRM_SF	<1..23	CDD:302621	8/21 (38%)
		RRM2_I_PABPs	29..105	CDD:240825	40/75 (53%)
		ELAV_HUD_SF	30..296	CDD:273741	130/276 (47%)
		RRM3_I_PABPs	118..197	CDD:240826	41/79 (52%)
		RRM4_I_PABPs	222..299	CDD:240827	41/76 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	89	1.000	Domainoid score	I2686
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.990