DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pAbp and PAB3

DIOPT Version :9

Sequence 1:	NP_476667.1	Gene:	pAbp / 37070	FlyBaseID:	FBgn0265297	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_173690.1	Gene:	PAB3 / 838882	AraportID:	AT1G22760	Length:	660	Species:	Arabidopsis thaliana

Alignment Length:	645	Identity:	282/645 - (43%)
Similarity:	391/645 - (60%)	Gaps:	68/645 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFD 66
            :|||.|||...|.|:.|||.|.....|:|:|||||. .||||||||:||..|.||.||::.:|:.
plant    49 SSLYAGDLDPKVTEAHLFDLFKHVANVVSVRVCRDQ-NRRSLGYAYINFSNPNDAYRAMEALNYT 112

  Fly    67 LVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKG 131
            .:.::|||||.|.||||.|.||.||:||||||.:|||||:::|||:||.|||||||.|..|.|||
plant   113 PLFDRPIRIMLSNRDPSTRLSGKGNIFIKNLDASIDNKALFETFSSFGTILSCKVAMDVTGRSKG 177

  Fly   132 YGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDD 196
            ||||.||.||:|..:|||:||||:|.|:|:||.||.|:||.::.......||||||||..::..:
plant   178 YGFVQFEKEESAQAAIDKLNGMLMNDKQVFVGHFIRRQERARDENTPTPRFTNVYVKNLPKEIGE 242

  Fly   197 EKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQK 261
            ::|::.|..:|.|:|..||..:.|.|:.||||.||.||||.:||:.:||..:|: ..|||.||||
plant   243 DELRKTFGKFGVISSAVVMRDQSGNSRCFGFVNFECTEAAASAVEKMNGISLGD-DVLYVGRAQK 306

  Fly   262 KAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRS 326
            |:||::||:||||:.:..|.|...|.|||:|||||::||::|:..||.|||:||:|||.:.:|.|
plant   307 KSEREEELRRKFEQERINRFEKSQGANLYLKNLDDSVDDEKLKEMFSEYGNVTSSKVMLNPQGMS 371

  Fly   327 KGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQI 391
            :|||||.::...||..|::|:||:::|.||||:|||||||:|:|||.:.:            .||
plant   372 RGFGFVAYSNPEEALRALSEMNGKMIGRKPLYIALAQRKEDRRAHLQALF------------SQI 424

  Fly   392 YQPNAASGFFVP-----TLPSNQRFFGSQVATQMRNTP---RWVPQVRPPAAIQGVQAGAAAAGG 448
            ..|...|||..|     ..|....:.|...|:.:.:.|   .:.||..|     |::.| :..|.
plant   425 RAPGPMSGFHHPPGGPMPGPPQHMYVGQNGASMVPSQPIGYGFQPQFMP-----GMRPG-SGPGN 483

  Fly   449 FQGTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITGQQTAAPNMQIPGAQIA 513
            |     .||...:        .|||..........|.|::    :.|..||....|.. ||.:..
plant   484 F-----IVPYPLQ--------RQPQTGPRMGFRRGATNVQ----QHIQQQQLMHRNPS-PGMRYM 530

  Fly   514 GGAQQRTSNYKYTSNMRN---PPVPQ--LHQTQPIPQQLQGKNSEKL-------IASLLANAKPQ 566
            .||          ||.||   ..|||  |....|:|......:.:|.       :.|.||:|.|.
plant   531 NGA----------SNGRNGMDSSVPQGILPPIIPLPIDASSISHQKAPLLPISKLTSSLASASPA 585

  Fly   567 EQKQILGERLYPMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQV 626
            ::.::|||:|||::|........|:||||||::.:|:||::|..||||:||.||:.||::
plant   586 DRTRMLGEQLYPLVERHEPLHVAKVTGMLLEMDQAEILHLMESPEALKSKVSEALDVLRL 645

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	281/642 (44%)
PAB3	NP_173690.1	PABP-1234	49..644	CDD:130689	281/642 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	103	1.000	Domainoid score	I2252
eggNOG	1	0.900	-	-		E1_KOG0123
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37855
Inparanoid	1	1.050	490	1.000	Inparanoid score	I329
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		otm2763
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840