DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pAbp and PAB4

DIOPT Version :9

Sequence 1:	NP_476667.1	Gene:	pAbp / 37070	FlyBaseID:	FBgn0265297	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_179916.1	Gene:	PAB4 / 816867	AraportID:	AT2G23350	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	667	Identity:	282/667 - (42%)
Similarity:	380/667 - (56%)	Gaps:	106/667 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNF 65
            :.|||||||..:|.:|.|:|.|:....|:|:|||||..|..||||.|||:....|||:|:..:|:
plant    45 LCSLYVGDLDFNVTDSQLYDYFTEVCQVVSVRVCRDAATNTSLGYGYVNYSNTDDAEKAMQKLNY 109

  Fly    66 DLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSK 130
            ..:..|.|||.:|.||.|.|||||||:|:||||:::|||.:::.||..|.|:|||||||..|.|:
plant   110 SYLNGKMIRITYSSRDSSARRSGVGNLFVKNLDKSVDNKTLHEAFSGCGTIVSCKVATDHMGQSR 174

  Fly   131 GYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFD 195
            |||||.|:||::|..:|:|:||.:||.|:::||.|: |||..:...:|.| ||||||||.:|...
plant   175 GYGFVQFDTEDSAKNAIEKLNGKVLNDKQIFVGPFL-RKEERESAADKMK-FTNVYVKNLSEATT 237

  Fly   196 DEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQ 260
            |::||..|..||.|:|..||...||||:.||||.||..|.|..||:|||||.. :.|..||.:||
plant   238 DDELKTTFGQYGSISSAVVMRDGDGKSRCFGFVNFENPEDAARAVEALNGKKF-DDKEWYVGKAQ 301

  Fly   261 KKAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGR 325
            ||:||:.||.|::|:..........|:||||||||||:.|::||..|:.:|.|||.|||.|..|.
plant   302 KKSERELELSRRYEQGSSDGGNKFDGLNLYVKNLDDTVTDEKLRELFAEFGTITSCKVMRDPSGT 366

  Fly   326 SKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQ 390
            |||.|||.|:|||||:..:.|:||::||.||||||||||||||:|.|.:|:
plant   367 SKGSGFVAFSAASEASRVLNEMNGKMVGGKPLYVALAQRKEERRAKLQAQF-------------- 417

  Fly   391 IYQPNAASGFFVPTLPSNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAG-----GFQ 450
                                       :|||  |.::|.|.|...|  ...||...|     | |
plant   418 ---------------------------SQMR--PAFIPGVGPRMPI--FTGGAPGLGQQIFYG-Q 450

  Fly   451 GTAGAVPTQ------------FRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITG-----Q 498
            |....:|.|            .|.|..|....||..||.          |..|.|:..|     .
plant   451 GPPPIIPHQPGFGYQPQLVPGMRPAFFGGPMMQPGQQGP----------RPGGRRSGDGPMRHQH 505

  Fly   499 QTAAPNMQ---IPGAQIAGGAQQRTSNYKYTSNMRNPP--------VPQLHQTQPIPQQLQGKNS 552
            |...|.||   :|          |...|:|.|..||.|        ||..:....:|.. |..::
plant   506 QQPMPYMQPQMMP----------RGRGYRYPSGGRNMPDGPMPGGMVPVAYDMNVMPYS-QPMSA 559

  Fly   553 EKLIASLLANAKPQEQKQILGERLYPMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKV 617
            .:| |:.||||.|.:|:.:|||.|||:::.:.:..|.|:||||||::.:|:||::|..|||.|||
plant   560 GQL-ATSLANATPAQQRTLLGESLYPLVDQIESEHAAKVTGMLLEMDQTEVLHLLESPEALNAKV 623

  Fly   618 EEAVAVLQVHRVTEPAN 634
            .||:.||:  .|.:|::
plant   624 SEALDVLR--NVNQPSS 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	279/655 (43%)
PAB4	NP_179916.1	PABP-1234	47..631	CDD:130689	279/654 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	89	1.000	Domainoid score	I2686
eggNOG	1	0.900	-	-		E1_KOG0123
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	490	1.000	Inparanoid score	I329
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		otm2763
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840