Protein Alignment pAbp and PABPC1L

DIOPT Version :9

• Sequence 1: NP_476667.1
• Gene: pAbp / 37070
• FlyBaseID: FBgn0265297
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001359108.1
• Gene: PABPC1L / 80336
• HGNCID: 15797
• Length: 619
• Species: Homo sapiens
• Alignment Length: 639
• Identity: 347/639 - (54%)
• Similarity: 429/639 - (67%)
• Gaps: 44/639 - (6%)

  Fly     1 MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNF 65
            :||||||||..||.|:.|::|||.|||:|||||||||.|||||||||:|||||||||||||||||
Human    10 LASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNF 74

  Fly    66 DLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSK 130
            ::::.:|||||||||||.||:|||||:|||||:.:|||||:|||||.||||||||||.||.| |:
Human    75 EMLKGQPIRIMWSQRDPGLRKSGVGNIFIKNLEDSIDNKALYDTFSTFGNILSCKVACDEHG-SR 138

  Fly   131 GYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFD 195
            |:|||||||.|||..:|:.:||||||.:||:||.|..|:|||.|||.:|..|||:||||...|.|
Human   139 GFGFVHFETHEAAQQAINTMNGMLLNDRKVFVGHFKSRREREAELGARALEFTNIYVKNLPVDVD 203

  Fly   196 DEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQ 260
            ::.|::.|..:||:.|.|||....|.|:.||||.||..|.|:.||..:|||:: .|:.||..|||
Human   204 EQGLQDLFSQFGKMLSVKVMRDNSGHSRCFGFVNFEKHEEAQKAVVHMNGKEV-SGRLLYAGRAQ 267

  Fly   261 KKAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGR 325
            |:.|||.||||:||::||.|.....|||||||||||:||||:||..|||||.|||||||| |.|.
Human   268 KRVERQNELKRRFEQMKQDRLRRYQGVNLYVKNLDDSIDDDKLRKEFSPYGVITSAKVMT-EGGH 331

  Fly   326 SKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQ--- 387
            |||||||||::..|||.||||:|||:||:||||||||||||||||.|.:|||:.::.||...
Human   332 SKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYMQRLSTMRTLSNPL 396

  Fly   388 LGQIYQPNAASGFFVPTL---PSNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGF 449
            ||...||   |.:|:|.:   |:...::|....|..:..|||..|  ||........||:..
Human   397 LGSFQQP---SSYFLPAMPQPPAQAAYYGCGPVTPTQPAPRWTSQ--PPRPSSAYPPGASMV--- 453

  Fly   450 QGTAGAVPTQFRSAAAGARGAQPQVQGT--HAAAAAANNMRNTGARAITGQQTAAPNMQIPGAQI 512
              ....||.:..:..:..|.|..||..|  |....|....:.||.   :|.....|...:...:.
Human   454 --RPPVVPRRPPAHISSVRQASTQVPRTVPHTQRVANIGTQTTGP---SGVGCCTPGRPLLPCKC 513

  Fly   513 AGGAQQRTSNYKYTSNMRNPPVPQLHQTQPIPQQLQGKNSEKLIASLLANAKPQEQKQILGERLY 577
            :..|.   |.|:...       |.:|    ||.|      |.|.||:||.|...||||::|||||
Human   514 SSAAH---STYRVQE-------PAVH----IPGQ------EPLTASMLAAAPLHEQKQMIGERLY 558

  Fly   578 PMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQVHRVTE 631
            |:|..:|..||||||||||||:|||||.|:|..|:|.||::|||||||.|:..|
Human   559 PLIHDVHTQLAGKITGMLLEIDNSELLLMLESPESLHAKIDEAVAVLQAHQAME 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	343/630 (54%)
PABPC1L	NP_001359108.1	PABP-1234	11..606	CDD:130689	343/630 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	122	1.000	Domainoid score	I5639
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	703	1.000	Inparanoid score	I670
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		otm42134
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	11	10.980