Protein Alignment pAbp and Pabpc1l

DIOPT Version :9

• Sequence 1: NP_476667.1
• Gene: pAbp / 37070
• FlyBaseID: FBgn0265297
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001107551.1
• Gene: Pabpc1l / 381404
• MGIID: 1922908
• Length: 607
• Species: Mus musculus
• Alignment Length: 646
• Identity: 323/646 - (50%)
• Similarity: 412/646 - (63%)
• Gaps: 68/646 - (10%)

  Fly     1 MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNF 65
            ::|||||||..||.||.|::.||..|.:|||||||||.|||||||||:|||||||||||||||||
Mouse    10 LSSLYVGDLHPDVTESMLYEMFSPIGNILSIRVCRDVATRRSLGYAYINFQQPADAERALDTMNF 74

  Fly    66 DLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSK 130
            ::::.:|||||||.|||.||:||:||:|||||:.:|||||:|||||.||:|||.||..:|.| |:
Mouse    75 EVIKGQPIRIMWSHRDPGLRKSGMGNIFIKNLENSIDNKALYDTFSTFGSILSSKVVYNEHG-SR 138

  Fly   131 GYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFD 195
            |:|||||||.|||..:|:.:||||||.:||:||.|..|::||.|||.:|..|||:||||...:.|
Mouse   139 GFGFVHFETHEAAQKAINTMNGMLLNDRKVFVGHFKSRQKREAELGARALGFTNIYVKNLHANVD 203

  Fly   196 DEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQ 260
            :::|::.|..:|.:.|.|||...:|:|:|||||.||..|.|:.||..:|||:: .|:.|||.|||
Mouse   204 EQRLQDLFSQFGNMQSVKVMRDSNGQSRGFGFVNFEKHEEAQKAVDHMNGKEV-SGQLLYVGRAQ 267

  Fly   261 KKAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGR 325
            |:||||.||||:||::||:|.....|||||||||||:|:|:||:..||.||.|||||||| |...
Mouse   268 KRAERQSELKRRFEQMKQERQNRYQGVNLYVKNLDDSINDERLKEVFSTYGVITSAKVMT-ESSH 331

  Fly   326 SKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQ 390
            |||||||||::..|||.||||:|||:||:||||||||||||||||.|.:||.|..:   ...|..
Mouse   332 SKGFGFVCFSSPEEATKAVTEMNGRIVGTKPLYVALAQRKEERKAILTNQYRRRPS---HPVLSS 393

  Fly   391 IYQPNAASGFFVPTLPSNQR---FFGSQVATQMRNTPRWV------PQVRPPAA-----IQGVQA 441
            ..||   :.:.:|.:|.:..   ::.|...|.|:..|||.      |...||||     :...|.
Mouse   394 FQQP---TSYLLPAVPQSTAQAVYYSSGSITPMQPDPRWTAQPHGPPSTCPPAASVVQPLSTTQH 455

  Fly   442 GAAAAGGFQGTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGA-RAITGQQTAAPNM 505
            ......|....:..||...|....|.:...|..:|:..........|.|.| .:..|.|.:|  :
Mouse   456 PCIHLRGASQVSSQVPHTQRVVNIGTQTTGPGGEGSSIPGQLLVPHRGTSAVHSAHGVQESA--V 518

  Fly   506 QIPGAQIAGGAQQRTSNYKYTSNMRNPPVPQLHQTQPIPQQLQGKNSEKLIASLLANAKPQEQKQ 570
            .:||                            ||              .|..|:||.|...||||
Mouse   519 YVPG----------------------------HQ--------------PLTVSMLAAAPLHEQKQ 541

  Fly   571 ILGERLYPMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVAVLQVHRVTE 631
            ::|||||.:|....|.|.|||||||||::|.|||.::|..|:|.||:|||||||||||..|
Mouse   542 MIGERLYSLIHDACAPLTGKITGMLLELDNLELLLLLESPESLHAKIEEAVAVLQVHREME 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	317/637 (50%)
Pabpc1l	NP_001107551.1	PABP-1234	11..596	CDD:130689	317/637 (50%)
		RRM1_I_PABPs	12..91	CDD:240824	58/78 (74%)
		RRM2_I_PABPs	97..172	CDD:240825	49/75 (65%)
		RRM3_I_PABPs	190..269	CDD:240826	38/79 (48%)
		RRM4_I_PABPs	293..370	CDD:240827	57/77 (74%)
		PABP	529..595	CDD:279051	39/65 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I5666
eggNOG	1	0.900	-	-		E1_KOG0123
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53624
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.780