DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pAbp and Pabpc4l

DIOPT Version :9

Sequence 1:	NP_476667.1	Gene:	pAbp / 37070	FlyBaseID:	FBgn0265297	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001099899.1	Gene:	Pabpc4l / 295010	RGDID:	1559517	Length:	370	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	206/363 - (56%)
Similarity:	273/363 - (75%)	Gaps:	3/363 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFD 66
            ||||||||.:||.|..||.||::.|||||||:|||:|:.|||||.||||.|..||::||:|||||
  Rat    10 ASLYVGDLHEDVTEDLLFRKFNTVGPVLSIRICRDLISHRSLGYGYVNFLQVGDAQKALETMNFD 74

  Fly    67 LVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKG 131
            |::.|.||:||||||..||:||:|||||||||::||||.:|:.||.||.|:|.||.|||:| |||
  Rat    75 LIKGKSIRLMWSQRDACLRKSGIGNVFIKNLDKSIDNKTLYEHFSPFGKIMSSKVMTDEEG-SKG 138

  Fly   132 YGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDD 196
            |||||::.:.||:.:|:::||.||....::|.:|..||:||.||.||...|||||:|||.:|.||
  Rat   139 YGFVHYQDQRAADRAIEEMNGKLLRDSTLFVARFKSRKDREAELREKPAEFTNVYIKNFGDDMDD 203

  Fly   197 EKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQK 261
            |.|:..|..||:..|.|||....||||.||||:|::.:||:.||:.:||:|: .|::::|.||||
  Rat   204 ESLRSVFSKYGQTLSVKVMKDASGKSKRFGFVSFDSHKAAKNAVEDMNGRDI-NGQTIFVGRAQK 267

  Fly   262 KAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRS 326
            |.|||.|||..||::|::|..:.....||:|||||||||:.||..||.:|:|...||| .|.|:|
  Rat   268 KVERQAELKEMFEQMKKERIRARQAAKLYIKNLDDTIDDETLRKEFSVFGSICRVKVM-QEAGQS 331

  Fly   327 KGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQR 364
            ||||.:||.:...|..|:.|:|||::|||||.:||.|:
  Rat   332 KGFGLICFFSPEAAAKAMAEMNGRILGSKPLNIALGQK 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	206/363 (57%)
Pabpc4l	NP_001099899.1	ELAV_HUD_SF	11..262	CDD:273741	146/252 (58%)
		RRM1_I_PABPs	11..89	CDD:240824	52/77 (68%)
		RRM2_I_PABPs	96..171	CDD:240825	43/75 (57%)
		RRM3_I_PABPs	189..268	CDD:240826	41/79 (52%)
		RRM_SF	293..369	CDD:302621	42/76 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I8281
eggNOG	1	0.900	-	-		E1_KOG0123
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.880