Protein Alignment pAbp and pabp

DIOPT Version :9

• Sequence 1: NP_476667.1
• Gene: pAbp / 37070
• FlyBaseID: FBgn0265297
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_593377.1
• Gene: pabp / 2541505
• PomBaseID: SPAC57A7.04c
• Length: 653
• Species: Schizosaccharomyces pombe
• Alignment Length: 660
• Identity: 289/660 - (43%)
• Similarity: 376/660 - (56%)
• Gaps: 119/660 - (18%)

  Fly     2 ASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNFD 66
            ||||||:|...|.|:.||:.|:|.|||.|||||||.:||||||||||||....|.|:|||.:|:.
pombe    80 ASLYVGELDPSVTEAMLFELFNSIGPVASIRVCRDAVTRRSLGYAYVNFHNMEDGEKALDELNYT 144

  Fly    67 LVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSKG 131
            |::.:|.||||||||||||:.|.|||||||||.||||||::|||||||.|||||||.||.||:||
pombe   145 LIKGRPCRIMWSQRDPSLRKMGTGNVFIKNLDPAIDNKALHDTFSAFGKILSCKVAVDELGNAKG 209

  Fly   132 YGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFDD 196
            ||||||::.|:||.:|:.|||||||.||||||..:.|:||:.::......|||||:||...:..:
pombe   210 YGFVHFDSVESANAAIEHVNGMLLNDKKVYVGHHVSRRERQSKVEALKANFTNVYIKNLDTEITE 274

  Fly   197 EKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDMGEGKSLYVARAQK 261
            ::..:.|..:|:|||..::..::.|.:|||||.:...|.|:.||..||.|:. :||.|||.||||
pombe   275 QEFSDLFGQFGEITSLSLVKDQNDKPRGFGFVNYANHECAQKAVDELNDKEY-KGKKLYVGRAQK 338

  Fly   262 KAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEGRS 326
            |.||::||::::|::|.::.....||||::|||.|.:||:||:..||.:|.|||||:||||:|:|
pombe   339 KHEREEELRKRYEQMKLEKMNKYQGVNLFIKNLQDEVDDERLKAEFSAFGTITSAKIMTDEQGKS 403

  Fly   327 KGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQLGQI 391
            |||||||:....||..||||:|.|::..||||||||||||.|::.|.:|
pombe   404 KGFGFVCYTTPEEANKAVTEMNQRMLAGKPLYVALAQRKEVRRSQLEAQ---------------- 452

  Fly   392 YQPNAASGFFVPTLPSNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAA-----AAGGFQG 451
                                      .|.||..|...||...|.|..||.||.     ..||:
pombe   453 --------------------------IQARNQFRLQQQVAAAAGIPAVQYGATGPLIYGPGGY-- 489

  Fly   452 TAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITGQQTAAPNM--QIPGAQIAG 514
               .:|     ||...|| .|.|.|.:                  |.....|.|  |.|    ||
pombe   490 ---PIP-----AAVNGRG-MPMVPGHN------------------GPMPMYPGMPTQFP----AG 523

  Fly   515 GAQQRTSNYKYTSNMRNPPVPQLHQTQPIPQQ-----LQGK-----------------NSEKLIA 557
            |..              |..|.::...|:|.|     :.|.                 ..|:..|
pombe   524 GPA--------------PGYPGMNARGPVPAQGRPMMMPGSVPSAGPAEAEAVPAVPGMPERFTA 574

  Fly   558 SLLANAKPQEQKQILGERLYPMIEHMHANLAGKITGMLLEIENSELLHMIEDQEALKAKVEEAVA 622
            :.||....:.:||:|||.|||.:......|:|||||||||:.|||||.::||..||..:|.||:.
pombe   575 ADLAAVPEESRKQVLGELLYPKVFVREEKLSGKITGMLLEMPNSELLELLEDDSALNERVNEAIG 639

  Fly   623 VLQVHRVTEP 632
            |||.....||
pombe   640 VLQEFVDQEP 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	285/651 (44%)
pabp	NP_593377.1	PABP-1234	80..642	CDD:130689	285/651 (44%)
		RRM1_I_PABPs	81..160	CDD:240824	49/78 (63%)
		RRM2_I_PABPs	166..242	CDD:240825	58/75 (77%)
		RRM3_I_PABPs	260..339	CDD:240826	33/79 (42%)
		RRM4_I_PABPs	363..441	CDD:240827	49/77 (64%)
		PolyA	581..644	CDD:197769	33/62 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	112	1.000	Domainoid score	I1577
eggNOG	1	0.900	-	-		E1_KOG0123
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	493	1.000	Inparanoid score	I250
OMA	1	1.010	-	-		QHG53624
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		oto101995
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	1	1.100	-	-	LDO	PTHR24012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2216
SonicParanoid	1	1.000	-	-		X269
TreeFam	1	0.960	-	-
	13	12.860