DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pAbp and bru2

DIOPT Version :9

Sequence 1:	NP_476667.1	Gene:	pAbp / 37070	FlyBaseID:	FBgn0265297	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_001036356.1	Gene:	bru2 / 250811	FlyBaseID:	FBgn0262475	Length:	893	Species:	Drosophila melanogaster

Alignment Length:	464	Identity:	113/464 - (24%)
Similarity:	181/464 - (39%)	Gaps:	103/464 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   167 PRKEREKELGEKAKLFTNVYVKNFTEDFDDEKLKEFFEPYGKITSYKVM-SKEDGKSKGFGFVAF 230
            |...:::...:..|:|    |....:.:|:.:|::.||.:|.:.:..|: .|....|:|..||.:
  Fly   283 PDSIKDQPDADNIKMF----VGQIPKTWDETRLRQMFEQFGPVHTLNVLRDKVTSISRGCCFVTY 343

  Fly   231 ETTEAAEAAVQALNGKDMGEGKSLYVARAQKKAERQQELKRKFEELKQKRHESVFGVNLYVKNLD 295
            .|.:||..|..||:.....:|  ::.....|.|:.:...:||                |:|..|:
  Fly   344 YTRKAALRAQDALHNIKTLDG--MHHPIQMKPADSENRNERK----------------LFVGMLN 390

  Fly   296 DTIDDDRLRIAFSPYGNITSAKVMTDEEGRSKGFGFVCFNAASEATCAVTEL--NGRVVG-SKPL 357
            ....:..:|..|:.:|.|....|:.|:.|:|||..||.|.....|..|:..|  :..:.| |.||
  Fly   391 KKYTEADVRQLFTGHGTIEECTVLRDQAGQSKGCAFVTFATKQNAIGAIKALHQSQTMEGCSAPL 455

  Fly   358 YVALA--QRKEERKAHLASQYMRHMTGMRMQQLGQ---IYQPN-AASGFFVPTL----------P 406
            .|..|  |:::::|              :|||:..   |..|: |.:|...||:          |
  Fly   456 VVKFADTQKEKDQK--------------KMQQIHAFCGINTPSGATAGAATPTINAATALIAAPP 506

  Fly   407 SNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAGGFQGTAGAVPTQFRSAAAGARGAQ 471
            |..|...|..|....     ||||:        |||:||      ||........|..|.:....
  Fly   507 SAGRTNPSMAAALAA-----VPQVQ--------QAGSAA------TAPTTLVPLNSTTALSASLT 552

  Fly   472 PQVQGTHAA---AAAANNMRNTGARAITGQQTAAPNMQIPGAQIAGGAQQRTSNYKYTSNMRNPP 533
            |.:..|:||   ||||       |..:.....||.::|:  .|...|.....::|....|..:||
  Fly   553 PNLLATNAAHQGAAAA-------AAYLGADPAAAAHLQL--YQQLHGYGLSPAHYLPGLNFHHPP 608

  Fly   534 VPQLHQTQPIPQQLQGKNSEKLIASL-------LANAKPQEQKQILGERLYPMIEHMHANLAGKI 591
            ....|.:|..| .:.|.::..|.|:.       |..|.|....        |.....||..||.:
  Fly   609 ENSAHHSQHSP-GIGGASAASLSAAAATAASNPLGGAPPPTPT--------PTSSAGHAAGAGLL 664

  Fly   592 TGMLLEIEN 600
            ....:.::|
  Fly   665 AAPSMSMQN 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	113/464 (24%)
bru2	NP_001036356.1	RRM1_CELF1_2_Bruno	294..375	CDD:241075	22/86 (26%)
		RRM2_Bruno_like	381..461	CDD:241080	26/95 (27%)
		RRM_SF	801..892	CDD:302621
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010