Protein Alignment pAbp and pab-2

DIOPT Version :9

• Sequence 1: NP_476667.1
• Gene: pAbp / 37070
• FlyBaseID: FBgn0265297
• Length: 634
• Species: Drosophila melanogaster
• Sequence 2: NP_001379081.1
• Gene: pab-2 / 181473
• WormBaseID: WBGene00003903
• Length: 692
• Species: Caenorhabditis elegans
• Alignment Length: 660
• Identity: 348/660 - (52%)
• Similarity: 423/660 - (64%)
• Gaps: 76/660 - (11%)

  Fly     1 MASLYVGDLPQDVNESGLFDKFSSAGPVLSIRVCRDVITRRSLGYAYVNFQQPADAERALDTMNF 65
            |||||:|||..||:|:.||:|||.||||||||||||..:|.||||||||||||||||||||||||
 Worm    56 MASLYIGDLHPDVSEAMLFEKFSMAGPVLSIRVCRDNTSRLSLGYAYVNFQQPADAERALDTMNF 120

  Fly    66 DLVRNKPIRIMWSQRDPSLRRSGVGNVFIKNLDRAIDNKAIYDTFSAFGNILSCKVATDEKGNSK 130
            :::..:|:|||||||||:.||:|.||:|||||||.||||::|||||.||||||||||||::||||
 Worm   121 EVIHGRPMRIMWSQRDPAARRAGNGNIFIKNLDRVIDNKSVYDTFSLFGNILSCKVATDDEGNSK 185

  Fly   131 GYGFVHFETEEAANTSIDKVNGMLLNGKKVYVGKFIPRKEREKELGEKAKLFTNVYVKNFTEDFD 195
            ||||||||||.:|.|:|:|||||||:.||||||||.||.:|.|||||....:|||:||||.|..|
 Worm   186 GYGFVHFETEHSAQTAIEKVNGMLLSDKKVYVGKFQPRAQRMKELGESGLKYTNVFVKNFGEHLD 250

  Fly   196 DEKLKEFFEPYGKITSYKVMSKEDGKSKGFGFVAFETTEAAEAAVQALNGKDM-GEGKSLYVARA 259
            .|||...|..:|:|||..||:...||.||||||||...:||..||:.||...: |....|.|.||
 Worm   251 QEKLSAMFSKFGEITSAVVMTDAQGKPKGFGFVAFADQDAAGQAVEKLNDSILEGTDCKLSVCRA 315

  Fly   260 QKKAERQQELKRKFEELKQKRHESVFGVNLYVKNLDDTIDDDRLRIAFSPYGNITSAKVMTDEEG 324
            |||:||..|||||:|.|||:|.:...||||||||:::.::||.||..||.:|.|||||||.||.|
 Worm   316 QKKSERSAELKRKYEALKQERVQRYQGVNLYVKNIEEDLNDDGLRDHFSSFGTITSAKVMVDENG 380

  Fly   325 RSKGFGFVCFNAASEATCAVTELNGRVVGSKPLYVALAQRKEERKAHLASQYMRHMTGMRMQQ-- 387
            ||||||||||....|||.|||::|.:::|:||||||||||||:|:|.||||||:.:..:||.|
 Worm   381 RSKGFGFVCFEKPEEATAAVTDMNSKMIGAKPLYVALAQRKEDRRAQLASQYMQRLATLRMGQQA 445

  Fly   388 -----LGQIYQPNAASGFFVPTLPSNQRFFGSQVATQMRNTPRWVPQVRPPAAIQGVQAGAAAAG 447
                 :.|:||| ...|:|||. |.|                   .|.||     |.|..:|...
 Worm   446 SGVPAMTQLYQP-GQQGYFVPN-PMN-------------------AQGRP-----GFQPQSAQIR 484

  Fly   448 GFQGTAGAVPTQFRSAAAGARGAQPQVQGTHAAAAAANNMRNTGARAITG---QQTAAPNMQIPG 509
            |..|........|.......|...||.||...       ||....|...|   :...||.:..||
 Worm   485 GPPGQRVFQNQMFMQYPFNQRQVYPQQQGRPP-------MRTNDGRPQYGMAPRPAGAPRVGGPG 542

  Fly   510 AQIAG-----------GAQQRTSNYKYTSNMRNPP---VPQLHQTQPIP---QQLQGKN------ 551
            .|:.|           ||.|:..       .:.||   .||.|..||..   ||.||::
 Worm   543 VQMGGAPIRQQGPAPRGAPQKPF-------YQGPPRQQQPQQHSQQPAQQPGQQGQGQSGIVIHG 600

  Fly   552 SEKLIASLLANAKPQEQKQILGERLYPMIEHMHAN--LAGKITGMLLEIENSELLHMIEDQEALK 614
            .|.|.:.:||.|.||||||:||||:|.:||.|..|  .|||||||:|||:|:||:.|::|.|..:
 Worm   601 QETLTSHMLAQAAPQEQKQLLGERIYALIEKMFPNHKEAGKITGMMLEIDNAELIMMLQDAELFR 665

  Fly   615 AKVEEAVAVL 624
            :|||||..||
 Worm   666 SKVEEAFGVL 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pAbp	NP_476667.1	PABP-1234	2..625	CDD:130689	347/659 (53%)
pab-2	NP_001379081.1	PABP-1234	57..675	CDD:130689	345/657 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159446
Domainoid	1	1.000	121	1.000	Domainoid score	I3522
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	609	1.000	Inparanoid score	I497
Isobase	1	0.950	-	0	Normalized mean entropy	S574
OMA	1	1.010	-	-		QHG53624
OrthoDB	1	1.010	-	-		D1027234at2759
OrthoFinder	1	1.000	-	-		FOG0000294
OrthoInspector	1	1.000	-	-		otm14629
orthoMCL	1	0.900	-	-		OOG6_100425
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2216
SonicParanoid	1	1.000	-	-		X269
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.790