DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Pcl and PRHA

DIOPT Version :9

Sequence 1:	NP_001261067.1	Gene:	Pcl / 37069	FlyBaseID:	FBgn0003044	Length:	1043	Species:	Drosophila melanogaster
Sequence 2:	NP_194723.1	Gene:	PRHA / 829117	AraportID:	AT4G29940	Length:	796	Species:	Arabidopsis thaliana

Alignment Length:	711	Identity:	117/711 - (16%)
Similarity:	221/711 - (31%)	Gaps:	266/711 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   491 RQLPYHADKLSWDEK-----HRVNEEQIYC-YCGKPGKFDHNMLQCC--KCRNWFHTQCMQN--F 545
            |||...:...|.:||     ..::.:.|:| .|.....|..|.:..|  .|...||.:|:..  .
plant   164 RQLDLLSSVGSMEEKVIASDGSIHHDHIFCAECNSREAFPDNDIILCDGTCNRAFHQKCLDPPLE 228

  Fly   546 KKKLLRGDM--FFVFC-CTVCNNGIEFVRRMQIEWVDVLHIALYNLRKHQHQKYHHLLNDIWPFI 607
            .:.:..||.  |..|| |             :||.:|.::..:..         |..::..|..|
plant   229 TESIPPGDQGWFCKFCDC-------------KIEIIDTMNAQIGT---------HFPVDSNWQDI 271

  Fly   608 LEQRHQLPICEK--------WRT--------LPE--------------------------TAL-- 628
            ..:...|||..:        |.:        .||                          |:|
plant   272 FNEEASLPIGSEATVNNEADWPSDDSKDDDYDPEMRENGGGNSSNVSGDGGGDNDEESISTSLSL 336

  Fly   629 ----------------MERLKQTLKDYSDRFVCGREFKRAPAFYALRHSGPPHIPKVFLEPHEEL 677
                            :..:.:..:..::..|||...:|...:..|               :.|:
plant   337 SSDGVALSTGSWEGHRLSNMVEQCETSNEETVCGPRQRRTVDYTQL---------------YYEM 386

  Fly   678 --SDELLEKRFKLMLMPEEPDEGANELPKRVPKD--------VYEFNTDEDDPVETSE----DEI 728
              .|.:|:::..     |:.|.|.|:..||..:.        :.|.:..:.|.|||.|    |.:
plant   387 FGKDAVLQEQGS-----EDEDWGPNDRRKRKRESDAGSTLVTMCESSKKDQDVVETLEQSERDSV 446

  Fly   729 PI-------------KQIIEK-----AKKQAAQKADKH---DELPLKPDLAD------------- 759
            .:             :..:||     |:.:...||.:.   .||.|.|:..:
plant   447 SVENKGGRRRMFRLPRNAVEKLRQVFAETELPSKAVRDRLAKELSLDPEKVNKWFKNTRYMALRN 511

  Fly   760 ------------DNANDGDPG----------------KLPAPIPPLLDANSSRKRKAFRLSKRYD 796
                        ...:.||.|                .|...:||..||.:             .
plant   512 RKTESVKQPGDSKTVSGGDSGPEAVMENNTETNEVQDTLDDTVPPGFDATN-------------Q 563

  Fly   797 NSRNHCDLSSDENSSSSRGTSSLDLIIPPPVN----FLGRNNPFLMATPKKASQGRSISVGTGVG 857
            |..:.|:.:.:|....       ::..|.|.:    :|.:|:...:..|.: .|...||:.|.|.
plant   564 NILSPCNNNQEEFQQE-------NVSFPSPTDESQQYLEQNDSSFVLVPHE-KQSSEISLKTAVE 620

  Fly   858 VNGI-----------INSIFKLKGTSKEQPRMVRTIKRRLSAKDITIGPNQEVRRRRTRRLTTAI 911
            .|..           ::|...||..::|:....:.|:.          |::|:.|..:  |.||:
plant   621 ENETESKMMKEPHEELSSEMSLKTAAEEKETESKMIEE----------PHEELSREMS--LKTAV 673

  Fly   912 EVISTTT---------INPIPSHYLPIYAKDLQPPAPPMGKPTHGRLLRQRPQKQSPSQSRRNST 967
            |...|.:         :|...|....:..|:   ....|.:.:|..|..:...::  .::.|..|
plant   674 EEKETESKMMEEPHDELNSEMSLSTAVEEKE---TGSKMTEESHEELSNEMSLEE--KETGRKMT 733

  Fly   968 SSTATSSSSNGIGAPGHSMLDLKQSVNKYFGGAMNRIDAGEPFAIRAKRRMGNGQVQYLVE 1028
            ......:....:....:.:||:.|.::::          ..|   :.::::||.....|.|
plant   734 EEEELEAVMEMLCRTENKLLDVTQRLDRF----------KTP---KGRKKLGNSSSPLLEE 781

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Pcl	NP_001261067.1	TUDOR	350..399	CDD:197660
		PHD_SF	426..469	CDD:304600
		PHD2_MTF2_PHF19_like	514..565	CDD:276978	15/58 (26%)
		Mtf2_C	985..1032	CDD:290768	8/44 (18%)
PRHA	NP_194723.1	PHD_PRHA_like	192..244	CDD:276979	12/51 (24%)
		rad2	<386..>727	CDD:273166	65/383 (17%)
		homeodomain	454..506	CDD:238039	9/51 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12628
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100