Protein Alignment Pcl and mtf2

DIOPT Version :9

• Sequence 1: NP_001261067.1
• Gene: Pcl / 37069
• FlyBaseID: FBgn0003044
• Length: 1043
• Species: Drosophila melanogaster
• Sequence 2: NP_001038729.1
• Gene: mtf2 / 692292
• ZFINID: ZDB-GENE-060512-94
• Length: 605
• Species: Danio rerio
• Alignment Length: 720
• Identity: 195/720 - (27%)
• Similarity: 298/720 - (41%)
• Gaps: 203/720 - (28%)

  Fly   355 EDVFIKCNDGRFYLGTI--IDQTSDQYLIRFDDQSEQWCEPDKLRKLGGGSSITAGGGGASTTES 417
            :||..:.:||.||||||  ||:...:..:.|:|||:.|.    |.|     .|..|..|...
Zfish    50 QDVLARWSDGLFYLGTISKIDKHKHRCFVIFEDQSKSWV----LWK-----DIQTGDSGGEM--- 102

  Fly   418 TNTSPSGPMCVACKRSDIE--DVVEICERCGRGYHRGCTVEIVTGSGI-----WSCKRCAKPMKM 475
                    :|..|:....|  :.:.||::||:|||:.|...::..|.|     |.|::|
Zfish   103 --------LCSICQNESSEPPNEIVICDKCGQGYHQLCHAPVIDSSVIDSDDKWLCRQC------ 153

  Fly   476 QQPVSHKITKPAGICRQ-------------LPYHADKLSWDEKHRVNEEQIYCYCGKPGKFDHNM 527
               |....||..|..::             |||..::|.||:.|:.|.:|.|||||.||.:...|
Zfish   154 ---VFATTTKRGGALKKGPNAKALQEMKQSLPYALEELMWDQGHKTNIQQCYCYCGGPGDWYLKM 215

  Fly   528 LQCCKCRNWFHTQCMQNFKKKLLRGDMFFVFCCTVCNNGIEFVRRMQIEWVDVLHIALYNLRKHQ 592
            |||.||:.|||..|:|.|:|.:|.||.|::|.|:|||:|.|:.:|:.:.||||.|::||||....
Zfish   216 LQCNKCKQWFHEACIQCFQKPMLFGDRFYLFICSVCNSGPEYPKRLPLRWVDVAHLSLYNLSVIH 280

  Fly   593 HQKYHHLLNDIWPFILEQRHQLPICEKWRTLPETALMER---LKQTLKDYSDRFVCGREFKRAPA 654
            .:||.....::..:|.|...:|.:.|    |.||...||   :.:.|.:..|.|:.|:|.|:...
Zfish   281 KKKYFDSELELMTYINENWDRLQLGE----LAETPRAERYECILEALNNNLDMFMSGKEIKKKKH 341

  Fly   655 FYALRHSGPPHIPKVFLEPHEELSDELLEKRFKLMLMPEEPDEGANELPKRVPKDVYEFNTDEDD 719
            .:.||...|| .|:         |.|||..|        ||::.::|:..:..|
Zfish   342 LFGLRIRFPP-APQ---------SSELLSDR--------EPEKASHEIKIKGRK----------- 377

  Fly   720 PVETSEDEIPIKQIIEKAKKQAAQKADKHD-----ELPLKPDLADDNANDGDPGKLPAPIPPLLD 779
               .::..:....:...|.|:..:|...|.     :|....:|...|     .||.|......||
Zfish   378 ---ATKPPLSSMPVTNGAVKKGKRKYHTHSLETLAKLRRSSELLAQN-----DGKFPTIDNNSLD 434

  Fly   780 ANSSRKRKAFRLSKRYDNSRNHCDLSSDENSSSSRGTSSLDLIIPPPVNFLGRNNPFLMATPKKA 844
            ..:|:..|    |:.:..|.:..|:.|...:|:|..||:
Zfish   435 LMASKSAK----SETFLPSSSTSDVESVGATSTSETTST-------------------------- 469

  Fly   845 SQGRSISVGTGVGVNGIINSIFKLKGTSKEQPRMVR-TIKRRLSAKDITIGPNQEVRRRRTRRLT 908
            :..|..|:|:..|..           |....|.:.: .|||               ||.|.||.
Zfish   470 TLSRQSSLGSPSGPR-----------TGCFWPTITQPPIKR---------------RRGRPRRA- 507

  Fly   909 TAIEVISTTTINPIPSHYLPIYAKDLQPPAPPM-------GKPTHGRLLRQRPQKQSPSQSRRNS 966
                                     ||||.|.:       .:||...::.:      ||     :
Zfish   508 -------------------------LQPPNPEIPPASNTEPQPTTNNIIPE------PS-----A 536

  Fly   967 TSSTATSSSSNGIGAPGHSMLD-LKQSVNKYFGGAMNRIDAGEPFAIRAKRRMGNGQVQYLVEWG 1030
            ..|...||.....|...::.|: ||.|::.|||.| .|:..||.:.:.|:|...:|:|:|||||.
Zfish   537 LPSCLYSSMDIMQGLDPNTQLNHLKSSISTYFGAA-GRLACGEKYRVLARRITNDGKVEYLVEWE 600

  Fly  1031 GDTAT 1035
            |.||:
Zfish   601 GVTAS 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pcl	NP_001261067.1	TUDOR	350..399	CDD:197660	18/45 (40%)
		PHD_SF	426..469	CDD:304600	15/49 (31%)
		PHD2_MTF2_PHF19_like	514..565	CDD:276978	28/50 (56%)
		Mtf2_C	985..1032	CDD:290768	20/47 (43%)
mtf2	NP_001038729.1	TUDOR	44..95	CDD:197660	20/53 (38%)
		PHD1_MTF2	103..155	CDD:277053	16/60 (27%)
		PHD2_MTF2	202..253	CDD:277055	28/50 (56%)
		Mtf2_C	556..601	CDD:290768	20/45 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583823
Domainoid	1	1.000	47	1.000	Domainoid score	I12024
eggNOG	1	0.900	-	-		E1_KOG4323
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3332
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001586
OrthoInspector	1	1.000	-	-		otm25418
orthoMCL	1	0.900	-	-		OOG6_109707
Panther	1	1.100	-	-	O	PTHR12628
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1484
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.750