Protein Alignment Pcl and INTS12

DIOPT Version :9

• Sequence 1: NP_001261067.1
• Gene: Pcl / 37069
• FlyBaseID: FBgn0003044
• Length: 1043
• Species: Drosophila melanogaster
• Sequence 2: NP_001135943.1
• Gene: INTS12 / 57117
• HGNCID: 25067
• Length: 462
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 63/253 - (24%)
• Similarity: 89/253 - (35%)
• Gaps: 96/253 - (37%)

  Fly   217 QQPSP----IIPAI-------------QHKAILPL----IDSSTADSSSCSSSSVSSSSYSG--- 257
            |:|:|    :.||:             |....|..    :.:||..|.:.||:|||||..||
Human   228 QKPAPAVVSVTPAVKDPLVKKPETKLKQETTFLAFKRTEVKTSTVISGNSSSASVSSSVTSGLTG 292

  Fly   258 ----TATTSAAVVIVDEPDSTTTTPQTPPTTPEAMSSP-GKSSPSPPLLATQSLLKGVNSMKPSF 317
                .|.||:|.....:..|||......|.|..|...| |.:.     |||.|  ||....|
Human   293 WAAFAAKTSSAGPSTAKLSSTTQNNTGKPATSSANQKPVGLTG-----LATSS--KGGIGSK--- 347

  Fly   318 KTVEAAPPTPPTPPSPPPPP---------------PAPPVAAPSPAVTYALQEDVFIKCNDGRFY 367
              :.:...|.||.|..||||               ....|..|||:
Human   348 --IGSNNSTTPTVPLKPPPPLTLGKTGLSRSVSCDNVSKVGLPSPS------------------- 391

  Fly   368 LGTIIDQTSDQYLIRFDDQSEQWCEPDKLRKLGGGSSITAGGGGASTTESTNTSPSGP 425
              :::..:|.|.                   .|.|:|.|:|..|::|:::|:.|.|.|
Human   392 --SLVPGSSSQL-------------------SGNGNSGTSGPSGSTTSKTTSESSSSP 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pcl	NP_001261067.1	TUDOR	350..399	CDD:197660	2/48 (4%)
		PHD_SF	426..469	CDD:304600	63/253 (25%)
		PHD2_MTF2_PHF19_like	514..565	CDD:276978
		Mtf2_C	985..1032	CDD:290768
INTS12	NP_001135943.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..132
		PHD_Int12	161..212	CDD:276976
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	301..462		42/180 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4323
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900