Protein Alignment Pcl and phf1

DIOPT Version :9

• Sequence 1: NP_001261067.1
• Gene: Pcl / 37069
• FlyBaseID: FBgn0003044
• Length: 1043
• Species: Drosophila melanogaster
• Sequence 2: XP_002665057.3
• Gene: phf1 / 100334345
• ZFINID: ZDB-GENE-100922-277
• Length: 504
• Species: Danio rerio
• Alignment Length: 705
• Identity: 167/705 - (23%)
• Similarity: 240/705 - (34%)
• Gaps: 242/705 - (34%)

  Fly   355 EDVFIKCNDGRFYLGTI--IDQTSDQYLIRFDDQSEQWCEPDKLRKLGGGSSITAGGGGASTTES 417
            |||..:.:||..|||.:  :|......||||:|.||.|.    |||  ...|.::||
Zfish     8 EDVLARWSDGLLYLGNVKRVDSVKQCCLIRFEDNSEFWV----LRK--DIHSFSSGG-------- 58

  Fly   418 TNTSPSGPMCVACKRSDIEDVVEICERCGRGYHRGC---TVEIVTGSGIWSCKRCAKPMKMQQPV 479
                  ..:|..|....:::.:..|.:|..|||..|   ::|.......|.|::|         |
Zfish    59 ------EEVCCICDSPPLKEPLVNCLKCRHGYHPECHTPSIEPEVDPNSWICRQC---------V 108

  Fly   480 SHKITKPAGICR-------------QLPYHADKLSWDEKHRVNEEQIYCYCGKPGKFDHNMLQCC 531
            ....||..|..:             :|||....|.||.:|..|::|.||||..||:::..||||.
Zfish   109 FAVATKRGGALKRGRFARLMQIMKVRLPYQLSSLDWDPQHLTNQQQCYCYCAGPGEWNLKMLQCG 173

  Fly   532 KCRNWFHTQCMQNFKKKLLRGDMFFVFCCTVCNNGIEFVRRMQIEWVDVLHIALYNLRKHQHQKY 596
            .|..|||..|.|...|.||.||.|:.|.|:||:||.|.|:|:.:.|||:.|:.||:|.....:||
Zfish   174 SCGQWFHEACTQCLSKPLLYGDRFYQFQCSVCSNGAESVQRLPMTWVDLAHLVLYHLSLCCKRKY 238

  Fly   597 HHLLNDIWPFILEQRHQLPICEKWRTLPETALMER---LKQTLKDYSDRFVCGREFKRAPAFYAL 658
            ....::|..|..|....|.:    .||.:|...:|   |...|..:.||||.|:|.|:....:.|
Zfish   239 FDFDHEIMSFANENWESLLL----GTLSDTPRQDRCQNLLNALNSHKDRFVSGKEIKKKKCLFGL 299

  Fly   659 RHSGPPHIPKVFLEPHEELSDELLEKRFKLMLMPEEPDEGANELPKRVPKDVYEFNTDEDDPVET 723
            :...||.:.          ||:          .|...::..|...:|.|..|     ........
Zfish   300 QVRAPPPLS----------SDQ----------SPFIAEQPINITHRRSPSSV-----SCQRRAVA 339

  Fly   724 SEDEIPIKQIIEKAKKQAAQKADKHDELPLKPDLADDNANDGDPGKLPAPIPPLLDANSSRKRKA 788
            .:...|.:::.|.....|...||..|.:|
Zfish   340 PDVRKPKRRVTETQSCPAGVAADALDRVP------------------------------------ 368

  Fly   789 FRLSKRYDNSRNHCDLSSDENSSSSRGTSSLDLIIPPPVNFLGRNNPFLMATPKKASQGRSISVG 853
              ..:.|:.|..:.....||..|                         |.:.||:
Zfish   369 --CCRGYEGSNLYNSRKPDEEMS-------------------------LGSPPKR---------- 396

  Fly   854 TGVGVNGIINSIFKLKGTSKEQPRMVRTIKRRLSAKDITIGPNQEVRRRRTRRLTTAIEVISTTT 918
                       :|.|...|....:.:.......||:|
Zfish   397 -----------MFALYHPSYNASQDLSRALHHYSAED---------------------------- 422

  Fly   919 INP--IPSHYLPIYAKDLQPPA------PPMGKPTHGRLLRQRPQKQSPSQSRRNSTSSTATSSS 975
              |  :|:..||........||      |.:       .||..|...||.
Zfish   423 --PCGLPAPCLPCSVSSAHAPAQRYESCPSL-------FLRDVPPFHSPV--------------- 463

  Fly   976 SNGIGAPGHSMLDLKQSVNKYFGGAMNRIDAGEPFAIRAKRRMGNGQVQYLVEWG 1030
              |:.||. ||           |.|     .|:...|.|:|...:|::|||||||
Zfish   464 --GMAAPS-SM-----------GWA-----GGDAVRILARRVTADGKLQYLVEWG 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pcl	NP_001261067.1	TUDOR	350..399	CDD:197660	19/45 (42%)
		PHD_SF	426..469	CDD:304600	11/45 (24%)
		PHD2_MTF2_PHF19_like	514..565	CDD:276978	26/50 (52%)
		Mtf2_C	985..1032	CDD:290768	16/46 (35%)
phf1	XP_002665057.3	TUDOR	6..53	CDD:197660	20/50 (40%)
		PHD_SF	61..107	CDD:304600	11/45 (24%)
		PHD_SF	156..207	CDD:304600	26/50 (52%)
		Mtf2_C	<474..500	CDD:290768	13/31 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3332
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001586
OrthoInspector	1	1.000	-	-		otm25418
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12628
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1484
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.060