Protein Alignment Hsf and SKN7

DIOPT Version :9

• Sequence 1: NP_001036555.1
• Gene: Hsf / 37068
• FlyBaseID: FBgn0001222
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_012076.3
• Gene: SKN7 / 856613
• SGDID: S000001249
• Length: 622
• Species: Saccharomyces cerevisiae
• Alignment Length: 695
• Identity: 143/695 - (20%)
• Similarity: 250/695 - (35%)
• Gaps: 226/695 - (32%)

  Fly    39 AAAIGSGVPA--FLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFI 101
            :|..|:..||  |:.||:|::::.:...::.||::|:|||:.:..:|...:||.::||:|.|||:
Yeast    75 SANAGAKAPANEFVRKLFRILENNEYPDIVTWTENGKSFVVLDTGKFTTHILPNHFKHSNFASFV 139

  Fly   102 RQLNMYGFHKI--TSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRKI--------------- 149
            ||||.|.|||:  :..:....::.....||.||.|:.:....||.|||||
Yeast   140 RQLNKYDFHKVKRSPEERQRCKYGEQSWEFQHPEFRVHYGKGLDNIKRKIPAQRKVLLDESQKAL 204

  Fly   150 ------SNNKNGDDKGVLKPEAMSKILTDVKV-------MRGRQDNLDSRFSAMKQENEVLWREI 201
                  ..|.| :..|.|..|:.:::|....|       :|.|.|.|.......|.|:.....|:
Yeast   205 LHFNSEGTNPN-NPSGSLLNESTTELLLSNTVSKDAFGNLRRRVDKLQKELDMSKMESYATKVEL 268

  Fly   202 ASLRQKHAKQQQIVNKLIQFLITIVQPSRNMSGVKRHVQLMINNTPEIDRARTTSETESESGGGP 266
            ..|..|:       |.:|:.|||....:.|          ::||      ..|...|.:.:|
Yeast   269 QKLNSKY-------NTVIESLITFKTINEN----------LLNN------FNTLCSTLANNG--- 307

  Fly   267 VIHELREELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVDYSNQSVEDLLLQG 331
                :...:..:..|.:|.|.|                .|.:..:|.|:| :.:|
Yeast   308 ----IEVPIFGDNGNRNPTGNT----------------NPATTTAIQSNN-NTNN---------- 341

  Fly   332 NGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVTEAPDSHVQEVPNSPPYYEEQNVLTTPMVREQ 396
                         |||...:||                   .::||.|    :||.| ||..:..
Yeast   342 -------------ASPATSTVS-------------------LQLPNLP----DQNSL-TPNAQNN 369

  Fly   397 EQQKRQ------------QLKENNKLRRQAGDVILDAGD---------------ILVDSSSPK-- 432
            ....|:            .::..:|..|:.|..:....|               :|:|...|.
Yeast   370 TVTLRKGFHVLLVEDDAVSIQLCSKFLRKYGCTVQVVSDGLSAISTLEKYRYDLVLMDIVMPNLD 434

  Fly   433 -AQRTSIQHSTQPDVMVQPMIIKSEPENSSGLM--DLMT----PANDLYSVNFISEDMPTDIFED 490
             |..|||..|...:..:..|        :..:|  ||:|    ..||:.:..|..:|:      .
Yeast   435 GATATSIVRSFDNETPIIAM--------TGNIMNQDLITYLQHGMNDILAKPFTRDDL------H 485

  Fly   491 ALLPDGVEEAAKLDQQQKFGQSTVSSGKFASNFDVPTNSTLLDANQASTSKAAAKAQASEEEGMA 555
            ::|...:::...|.:||.                .|.||:  ....::|:.|.:......|:.:|
Yeast   486 SILIRYLKDRIPLCEQQL----------------PPRNSS--PQTHSNTNTANSNPNTINEQSLA 532

  Fly   556 VAKYS----------GAENGNNRDTNNSQLLRMASVLVDQKNTNSSRISHNQAANSYCCSDELHG 610
            :....          ||...:.:.....|..:...:...|:...    .||..||:.  ||..
Yeast   533 MLPQDNPSTTTPVTPGASISSAQHVQQGQQEQQHQIFHAQQQQQ----HHNAIANAR--SDVA-- 589

  Fly   611 HLESMQDELETLKDLLRGDGVAIDQNMLMGALSRTPNFQLPEDEL 655
             :.:::.|:.|:            .:..||:..:.|...|.|::|
Yeast   590 -IPNLEHEINTV------------PHSSMGSTPQLPQSTLQENQL 621

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	38/106 (36%)
		Vert_HS_TF	<607..711	CDD:284062	8/49 (16%)
SKN7	NP_012076.3	HSF1	75..350	CDD:227497	82/345 (24%)
		REC_hyHK_CKI1_RcsC-like	379..488	CDD:381099	21/122 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X160
TreeFam	1	0.960	-	-
	5	4.870