DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsf and HSFB4

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_175142.1	Gene:	HSFB4 / 841110	AraportID:	AT1G46264	Length:	348	Species:	Arabidopsis thaliana

Alignment Length:	345	Identity:	88/345 - (25%)
Similarity:	141/345 - (40%)	Gaps:	76/345 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 GSGVPA-FLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNM 106
            |..||| ||.|.::||||..|:.::.|..|..:||:....:||::|||..:||||.:||:||||.
plant    28 GKAVPAPFLTKTYQLVDDPATDHVVSWGDDDTTFVVWRPPEFARDLLPNYFKHNNFSSFVRQLNT 92

  Fly   107 YGFHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKG------------ 159
            |||.||..          |..||::.||||....||.:|.|:.::........
plant    93 YGFRKIVP----------DRWEFANEFFKRGEKHLLCEIHRRKTSQMIPQQHSPFMSHHHAPPQI 147

  Fly   160 --------------VLKPEAMSKILTDVKVMRGR----QDNLDSRFSAMKQENEVLWREIASLRQ 206
                          |..||.......|....|.|    |.:..::.:|:.::||.|.|....|..
plant   148 PFSGGSFFPLPPPRVTTPEEDHYWCDDSPPSRPRVIPQQIDTAAQVTALSEDNERLRRSNTVLMS 212

  Fly   207 KHAKQQQIVNKLIQFL---ITIVQPSRNMSGVKRHVQ-LMINNTPEIDRARTTSETESESGGGPV 267
            :.|..:::.|.:|.|:   :..|.||.|.|.:...:| ......|.:|...|.:...:..
plant   213 ELAHMKKLYNDIIYFVQNHVKPVAPSNNSSYLSSFLQKQQQQQPPTLDYYNTATVNATNL----- 272

  Fly   268 IHELREELLDEVMNPSPAGYTAA---------SHYDQESVSPP---AVERPRSNMSISSHNVDYS 320
                      ..:|.||....::         :|:||.::...   .|..|.|..  .||:  :|
plant   273 ----------NALNSSPPTSQSSITVLEDDHTNHHDQSNMRKTKLFGVSLPSSKK--RSHH--FS 323

  Fly   321 NQSVEDLLLQGNGTAGGNIL 340
            :|:.:..|:........|::
plant   324 DQTSKTRLVLDQSDLALNLM 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	45/103 (44%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSFB4	NP_175142.1	HSF	32..124	CDD:214654	44/101 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.880