DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsf and HSFA9

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_200218.1	Gene:	HSFA9 / 835493	AraportID:	AT5G54070	Length:	331	Species:	Arabidopsis thaliana

Alignment Length:	356	Identity:	86/356 - (24%)
Similarity:	146/356 - (41%)	Gaps:	107/356 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 EEEEDEEEQLPSR--RMHSYGDAAAIGSGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQA 81
            :||||:...|...  ::|..|       .:..||.|.:.:|||..|:.::.|:...:||:|.:..
plant    47 KEEEDDAVNLSLGFWKLHEIG-------LITPFLRKTFEIVDDKVTDPVVSWSPTRKSFIIWDSY 104

  Fly    82 QFAKELLPLNYKHNNMASFIRQLNMYGFHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIK 146
            :|::.|||..:||.|.:|||||||.|||.|:          |.|..||::..|:.....||..||
plant   105 EFSENLLPKYFKHKNFSSFIRQLNSYGFKKV----------DSDRWEFANEGFQGGKKHLLKNIK 159

  Fly   147 RKISNNKNGDDKGVLKPEAMSKILTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQK---- 207
            |:..|.|..:     |..:.:...|:|:.::..|..:......:||:.|....::.::::|
plant   160 RRSKNTKCCN-----KEASTTTTETEVESLKEEQSPMRLEMLKLKQQQEESQHQMVTVQEKIHGV 219

  Fly   208 -----H--------AKQQQIVNKLIQFLITIVQPSRNMSGVKRHVQLMINNTPEIDRARTTSETE 259
                 |        ||.|:.|.:|::        .|.|.     :|..:.....:.:.:...:.|
plant   220 DTEQQHMLSFFAKLAKDQRFVERLVK--------KRKMK-----IQRELEAAEFVKKLKLLQDQE 271

  Fly   260 SESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVD----YS 320
            ::           :.|||                         |||....|:.:.||.:    .:
plant   272 TQ-----------KNLLD-------------------------VEREFMAMAATEHNPEPDILVN 300

  Fly   321 NQS--------VEDLLLQGNGTAGGNILVGG 343
            |||        .||||:.     ||::.|.|
plant   301 NQSGNTRCQLNSEDLLVD-----GGSMDVNG 326

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	38/102 (37%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSFA9	NP_200218.1	HSF	71..161	CDD:214654	38/99 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.880