DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsf and RHA1

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_001331800.1	Gene:	RHA1 / 834610	AraportID:	AT5G45710	Length:	345	Species:	Arabidopsis thaliana

Alignment Length:	375	Identity:	84/375 - (22%)
Similarity:	167/375 - (44%)	Gaps:	73/375 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 SGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYG 108
            |.:|.||.|.:.:|||:.::.::.|:::.:||:::|.|:|:::|||..:||.|.:|||||||.||
plant     9 SSLPPFLTKTYEMVDDSSSDSVVAWSENNKSFIVKNPAEFSRDLLPRFFKHKNFSSFIRQLNTYG 73

  Fly   109 FHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKGVLKP---EAMSKIL 170
            |.|:          |.::.||.:..|.|..|:|:..|.|:             ||   .::..:.
plant    74 FRKV----------DPEKWEFLNDDFVRGRPYLMKNIHRR-------------KPVHSHSLVNLQ 115

  Fly   171 TDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPSRNMSGV 235
            ....:....:.:::.:...:|.|.|.|..|:.:..|:..          :|.:.:......:..:
plant   116 AQNPLTESERRSMEDQIERLKNEKEGLLAELQNQEQERK----------EFELQVTTLKDRLQHM 170

  Fly   236 KRHVQLMINNTPEI-DRARTTSETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVS 299
            ::|.:.::....:: .:...:...|:        ||.|:....|  |..|   .::||.:|
plant   171 EQHQKSIVAYVSQVLGKPGLSLNLEN--------HERRKRRFQE--NSLP---PSSSHIEQ---- 218

  Fly   300 PPAVERPRSNMSISSHNVDYSNQSVEDLLLQGNG---TAGGNILVGGAASPMAQSVSQSPAQHDV 361
               ||:..|:::...:.|   ::|.|...||.:.   .|..:.|..|...|.:..:..: ::..|
plant   219 ---VEKLESSLTFWENLV---SESCEKSGLQSSSMDHDAAESSLSIGDTRPKSSKIDMN-SEPPV 276

  Fly   362 YTVTEAPDSHVQEVPNSPPYYEEQNVLTTPMVREQEQ---QKRQQLKENN 408
            .....||.:.|.:      .:.||.:...|...||::   ::|....:||
plant   277 TVTAPAPKTGVND------DFWEQCLTENPGSTEQQEVQSERRDVGNDNN 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	38/102 (37%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
RHA1	NP_001331800.1	HSF	10..103	CDD:214654	38/102 (37%)
RHA1	NP_001331800.1	Flagellar_rod	107..>239	CDD:368306	23/164 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.880