DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsf and HSFA6A

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_199197.1	Gene:	HSFA6A / 834406	AraportID:	AT5G43840	Length:	282	Species:	Arabidopsis thaliana

Alignment Length:	204	Identity:	58/204 - (28%)
Similarity:	105/204 - (51%)	Gaps:	34/204 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 AFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYGFHKI 112
            |||.|.:.:|:|:.||.::.|::|..||::.....||...||..:||||.:||:||||.|||.||
plant    19 AFLTKTYNIVEDSSTNNIVSWSRDNNSFIVWEPETFALICLPRCFKHNNFSSFVRQLNTYGFKKI 83

  Fly   113 TSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRKISNNKNGDD--KGVLKPEAMSKILTDVKV 175
                      |.:..||::..|.:....||..|||:.::::....  :|.:......::..:|::
plant    84 ----------DTERWEFANEHFLKGERHLLKNIKRRKTSSQTQTQSLEGEIHELRRDRMALEVEL 138

  Fly   176 --MRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPS-------RN 231
              :|.:|:::.:....|:::          |:....||:.::|.|::   .|.:||       ||
plant   139 VRLRRKQESVKTYLHLMEEK----------LKVTEVKQEMMMNFLLK---KIKKPSFLQSLRKRN 190

  Fly   232 MSGVKRHVQ 240
            :.|:|...|
plant   191 LQGIKNREQ 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	39/99 (39%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSFA6A	NP_199197.1	HSF	16..109	CDD:214654	39/99 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.880