DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsf and HSFA3

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_001318473.1	Gene:	HSFA3 / 831749	AraportID:	AT5G03720	Length:	412	Species:	Arabidopsis thaliana

Alignment Length:	283	Identity:	74/283 - (26%)
Similarity:	118/283 - (41%)	Gaps:	71/283 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 GSGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMY 107
            |:.:|.||:|.:.||||...:.:|.|...|.|||:.:..:||:.:||.|:||||.:||:||||.|
plant    50 GNPIPPFLSKTFDLVDDPTLDPVISWGLTGASFVVWDPLEFARIILPRNFKHNNFSSFVRQLNTY 114

  Fly   108 GFHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKGVLKPEAMSKILTD 172
            ||.||          |.|:.||::..|.|....||..|.|:.|            |::.....:.
plant   115 GFRKI----------DTDKWEFANEAFLRGKKHLLKNIHRRRS------------PQSNQTCCSS 157

  Fly   173 VKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQ----------------KHAKQQQIVNKLIQF 221
            ....:|....:......:::|...|..|:..|:|                |.|:|:|  .:|:.|
plant   158 TSQSQGSPTEVGGEIEKLRKERRALMEEMVELQQQSRGTARHVDTVNQRLKAAEQRQ--KQLLSF 220

  Fly   222 LITIVQPSRNMSGVKRHVQLMINNTPEIDRARTTSETESESGGGPVIHELREELLDEVMNP--SP 284
            |..:.|                 |...::|.:...  ..|.||...:.:.|::.:.....|  ||
plant   221 LAKLFQ-----------------NRGFLERLKNFK--GKEKGGALGLEKARKKFIKHHQQPQDSP 266

  Fly   285 AGYTAASH----------YDQES 297
            .|.....:          ||:|:
plant   267 TGGEVVKYEADDWERLLMYDEET 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	43/102 (42%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSFA3	NP_001318473.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.880