DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsf and HSF3

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_197184.2	Gene:	HSF3 / 831545	AraportID:	AT5G16820	Length:	481	Species:	Arabidopsis thaliana

Alignment Length:	507	Identity:	114/507 - (22%)
Similarity:	192/507 - (37%)	Gaps:	141/507 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 EDEEEQLPSRRMHSYGDAAAIGSGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKE 86
            |...|.:||...::......:.| ||.||:|.:.:|||..||.::.|:....|||:.:..:|:|.
plant     2 ESVPESVPSPNSNTPSIPPPVNS-VPPFLSKTYDMVDDPLTNEVVSWSSGNNSFVVWSAPEFSKV 65

  Fly    87 LLPLNYKHNNMASFIRQLNMYGFHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQI-KRKIS 150
            |||..:||||.:||:||||.|||.|:          |.|..||::..|.|....||..| :||.|
plant    66 LLPKYFKHNNFSSFVRQLNTYGFRKV----------DPDRWEFANEGFLRGRKQLLKSIVRRKPS 120

  Fly   151 NNKNGDDKGVLKPEAMSKILTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQK-------- 207
            :.:....:..::..::...:...|.      .::.....:|::..||.:|:..|||:
plant   121 HVQQNQQQTQVQSSSVGACVEVGKF------GIEEEVERLKRDKNVLMQELVRLRQQQQATENQL 179

  Fly   208 ----------HAKQQQIVN---KLIQ---FLITIVQPSRNMSGVKRHVQLMINNTPEIDRARTTS 256
                      ..:|||:::   |.:|   ||..:||.:.|...         ...|..::.|...
plant   180 QNVGQKVQVMEQRQQQMMSFLAKAVQSPGFLNQLVQQNNNDGN---------RQIPGSNKKRRLP 235

  Fly   257 ETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVDYSN 321
            ..|.|:.|..|.:.|..:::                              |...||        |
plant   236 VDEQENRGDNVANGLNRQIV------------------------------RYQPSI--------N 262

  Fly   322 QSVEDLLLQGNGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVTEAPDSHVQEVPNSPPYYEEQN 386
            ::.:::|.|         .:..:.||..:|||.:|   |.:.:.:.|.|
plant   263 EAAQNMLRQ---------FLNTSTSPRYESVSNNP---DSFLLGDVPSS---------------- 299

  Fly   387 VLTTPMVREQEQQKRQQLKENNKLRRQAGDVILDAGDILVDSSSPKAQRTSIQHSTQPDVMVQPM 451
                           ..:...|...|.:|..:.:.....|.|::.:....|:.|..|.. :|||.
plant   300 ---------------TSVDNGNPSSRVSGVTLAEFSPNTVQSATNQVPEASLAHHPQAG-LVQPN 348

  Fly   452 IIKSEPENSSGLMDLMTPANDLYSVNFISEDMPTDIFE-------DALLPDG 496
            |.:| |...:...|..:|..||......|.:....|..       ||:.|:|
plant   349 IGQS-PAQGAAPADSWSPEFDLVGCETDSGECFDPIMAVLDESEGDAISPEG 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	42/103 (41%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSF3	NP_197184.2	HSF	24..117	CDD:214654	43/103 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	1	0.900	-	-		OOG6_101482
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.780