DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsf and HSF4

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_195416.1	Gene:	HSF4 / 829853	AraportID:	AT4G36990	Length:	284	Species:	Arabidopsis thaliana

Alignment Length:	250	Identity:	78/250 - (31%)
Similarity:	119/250 - (47%)	Gaps:	64/250 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 VPA-FLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYGF 109
            ||| ||:|.::||||..|:.::.|.::|.:||:...|:|||:|||..:||||.:|||||||.|||
plant    11 VPAPFLSKTYQLVDDHSTDDVVSWNEEGTAFVVWKTAEFAKDLLPQYFKHNNFSSFIRQLNTYGF 75

  Fly   110 HKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRK------------------ISNNKNGD 156
            .|...          |:.||::.:|:|....||..|:|:                  .||:..||
plant    76 RKTVP----------DKWEFANDYFRRGGEDLLTDIRRRKSVIASTAGKCVVVGSPSESNSGGGD 130

  Fly   157 DKG---------VLKPEAMSKILTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQ 212
            |.|         ...|.::..::.|   :.|..:.|       |:||..|..|:|:     ||:|
plant   131 DHGSSSTSSPGSSKNPGSVENMVAD---LSGENEKL-------KRENNNLSSELAA-----AKKQ 180

  Fly   213 QIVNKLIQFLI--TIVQPSRNMSGVKRHVQLMINNTPEIDRARTTSETESESGGG 265
            :  ::|:.||.  ..|:|.:....:|......:.:..|       ||.|...|||
plant   181 R--DELVTFLTGHLKVRPEQIDKMIKGGKFKPVESDEE-------SECEGCDGGG 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	45/102 (44%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSF4	NP_195416.1	HSF	12..104	CDD:214654	44/101 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.880