DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsf and AT-HSFA5

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_567415.1	Gene:	AT-HSFA5 / 827033	AraportID:	AT4G13980	Length:	466	Species:	Arabidopsis thaliana

Alignment Length:	516	Identity:	122/516 - (23%)
Similarity:	204/516 - (39%)	Gaps:	186/516 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 GSGVPA-FLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNM 106
            |:|.|| ||.|.:.:|||:.|::::.|:.:..||::.|.|:|::.|||..:||||.:|||||||.
plant    17 GAGGPAPFLVKTYEMVDDSSTDQIVSWSANNNSFIVWNHAEFSRLLLPTYFKHNNFSSFIRQLNT 81

  Fly   107 YGFHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRK--ISNNKNGDDKGVLKPEAMSKI 169
            |||.||          |.:..||.:..|.::...||..|.|:  |.::.:        |.|.|
plant    82 YGFRKI----------DPERWEFLNDDFIKDQKHLLKNIHRRKPIHSHSH--------PPASS-- 126

  Fly   170 LTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQK--HAKQQQIV----------------- 215
                         .|...:.::::.:.|.||.|::..|  ..|||::|
plant   127 -------------TDQERAVLQEQMDKLSREKAAIEAKLLKFKQQKVVAKHQFEEMTEHVDDMEN 178

  Fly   216 --NKLIQFLITIVQPSRNMSGV----KRHVQLMIN------NTPEIDRARTTSE---TESESG-- 263
              .||:.||.|.:   ||.:.|    |:..||.|:      ..||:::::..||   .::.||
plant   179 RQKKLLNFLETAI---RNPTFVKNFGKKVEQLDISAYNKKRRLPEVEQSKPPSEDSHLDNSSGSS 240

  Fly   264 ---GGPVIHE-----LREELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVDYS 320
               .|.:.|:     ||.||       |||.                     |:|::.||::..|
plant   241 RRESGNIFHQNFSNKLRLEL-------SPAD---------------------SDMNMVSHSIQSS 277

  Fly   321 NQSVEDLLLQGNGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVTEAPDSHVQEVPNSPPYYEEQ 385
            |:         .|.:...||.||..:.               |:|:.     :.:|.:|...|..
plant   278 NE---------EGASPKGILSGGDPNT---------------TLTKR-----EGLPFAPEALELA 313

  Fly   386 NVLTTPMVREQEQQKRQQLKENNKLR--------RQAGDVILDAGDILVDSSSPKAQRTSIQHST 442
            :..|.|        :|..|.:|.::.        .:..|........|..:|:|...:|:.|
plant   314 DTGTCP--------RRLLLNDNTRVETLQQRLTSSEETDGSFSCHLNLTLASAPLPDKTASQ--- 367

  Fly   443 QPDVMVQPMIIKSE-----------PENSSGLMDLMT---------PA--NDLYSVNFISE 481
                 :....:||:           .|.:.|..::..         ||  ||::...|::|
plant   368 -----IAKTTLKSQELNFNSIETSASEKNRGRQEIAVGGSQANAAPPARVNDVFWEQFLTE 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	42/103 (41%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
AT-HSFA5	NP_567415.1	HSF	24..113	CDD:214654	39/98 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.880