DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hsf and HSFA6B

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_188922.1	Gene:	HSFA6B / 821854	AraportID:	AT3G22830	Length:	406	Species:	Arabidopsis thaliana

Alignment Length:	375	Identity:	94/375 - (25%)
Similarity:	167/375 - (44%)	Gaps:	75/375 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 SGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYG 108
            ||.|.||.|.:.||:|:.||.::.|:|...||::.:...|:..|||..:||||.:||:||||.||
plant    57 SGPPPFLTKTYDLVEDSRTNHVVSWSKSNNSFIVWDPQAFSVTLLPRFFKHNNFSSFVRQLNTYG 121

  Fly   109 FHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQI-KRKISNNKNGDDKGVLKPEAMSKILTD 172
            |.|:          :.|..||::..|.|....||..| :||.|||.|    .:.:|::..:...|
plant   122 FRKV----------NPDRWEFANEGFLRGQKHLLKNIRRRKTSNNSN----QMQQPQSSEQQSLD 172

  Fly   173 VKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQP--SRNMSGV 235
            ...:...:..||....:::::.:||..|:..|||    |||..    :..:|:::.  .:..|..
plant   173 NFCIEVGRYGLDGEMDSLRRDKQVLMMELVRLRQ----QQQST----KMYLTLIEEKLKKTESKQ 229

  Fly   236 KRHVQLMINNTPEIDRARTTSETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSP 300
            |:.:..:.......|..:...|.:          |.|:|:                   :|::|.
plant   230 KQMMSFLARAMQNPDFIQQLVEQK----------EKRKEI-------------------EEAISK 265

  Fly   301 PAVERPRSNMSISSHNVDYSNQSVEDLLLQGNGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVT 365
            .. :||          :|...::|||   .|:.:..||.:...:::.:..|...:......:.::
plant   266 KR-QRP----------IDQGKRNVED---YGDESGYGNDVAASSSALIGMSQEYTYGNMSEFEMS 316

  Fly   366 EAPD--SHVQEVPNSPPYYEEQNVLTTPMVREQEQQKRQQL---KENNKL 410
            |...  .|:|.:.::....||  ||......::|:.:.||.   ||||::
plant   317 ELDKLAMHIQGLGDNSSAREE--VLNVEKGNDEEEVEDQQQGYHKENNEI 364

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	40/103 (39%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSFA6B	NP_188922.1	HSF	58..151	CDD:214654	40/102 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.880