DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Hsf and HSFA1E

DIOPT Version :9

Sequence 1:	NP_001036555.1	Gene:	Hsf / 37068	FlyBaseID:	FBgn0001222	Length:	733	Species:	Drosophila melanogaster
Sequence 2:	NP_186949.1	Gene:	HSFA1E / 821162	AraportID:	AT3G02990	Length:	468	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	118/522 - (22%)
Similarity:	201/522 - (38%)	Gaps:	136/522 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 AAAIGSGVPAFLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQ 103
            :.|:.|.:|.||:|.:.:|||..|:.::.|:....|||:.|..:|||:.||..:||||.:||:||
plant    14 STAVMSSIPPFLSKTYDMVDDPLTDDVVSWSSGNNSFVVWNVPEFAKQFLPKYFKHNNFSSFVRQ 78

  Fly   104 LNMYGFHKITSIDNGGLRFDRDEIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKGVLKPEAM-S 167
            ||.|||.|:          |.|..||::..|.|..    .||.:.|...|....:...:|:.. |
plant    79 LNTYGFRKV----------DPDRWEFANEGFLRGQ----KQILKSIVRRKPAQVQPPQQPQVQHS 129

  Fly   168 KILTDVKVMRGRQDNLDSRFSAMKQENEVLWREIASLRQKHAKQQQIV----------------- 215
            .:...|:|   .:..|:.....::::..||.:|:..|||    |||:.
plant   130 SVGACVEV---GKFGLEEEVERLQRDKNVLMQELVRLRQ----QQQVTEHHLQNVGQKVHVMEQR 187

  Fly   216 -NKLIQFLITIVQP-------SRNMSGVKRHVQLMINNTPEIDRARTTSETESESGGGPVIHELR 272
             .:::.||...||.       |:..:...:|:.       |.::.|.....:..:.|...::.|.
plant   188 QQQMMSFLAKAVQSPGFLNQFSQQSNEANQHIS-------ESNKKRRLPVEDQMNSGSHGVNGLS 245

  Fly   273 EELLDEVMNPSPAGYTAASHYDQESVSPPAVERPRSNMSISSHNVDYSNQSVEDLLLQGNGTAGG 337
            .:::....:.:.|..|......|.|.:|       |:.|:||:|..:....|.:..:..||::.
plant   246 RQIVRYQSSMNDATNTMLQQIQQMSNAP-------SHESLSSNNGSFLLGDVPNSNISDNGSSS- 302

  Fly   338 NILVGGAASPMAQSVSQSPAQHDVYTVTEAPDSHVQEVPNSPPYYEEQNVLTTPMVREQEQQKRQ 402
                .|:.......||..||                      .:|        |.::..|..:..
plant   303 ----NGSPEVTLADVSSIPA----------------------GFY--------PAMKYHEPCETN 333

  Fly   403 QLKENNKLRRQAGDVILDAGDILVDSSSPKAQRTSIQHSTQPDVMVQPMIIKSEPEN-------- 459
            |:.|.|        :....||:|     |..|..:...|:..|      ::..|.:|
plant   334 QVMETN--------LPFSQGDLL-----PPTQGAAASGSSSSD------LVGCETDNGECLDPIM 379

  Fly   460 ----------SSGLMDLMTPANDLYSVNFISEDMPTDIFEDALLPDGVEEAAKLDQQQKFGQSTV 514
                      :..|.:|:....|.:...||.|. |.....|.|:...||....|:|.:.  |||:
plant   380 AVLDGALELEADTLNELLPEVQDSFWEQFIGES-PVIGETDELISGSVENELILEQLEL--QSTL 441

  Fly   515 SS 516
            |:
plant   442 SN 443

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	40/102 (39%)
Hsf	NP_001036555.1	Vert_HS_TF	<607..711	CDD:284062
HSFA1E	NP_186949.1	HSF	20..113	CDD:214654	41/106 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	93	1.000	Domainoid score	I2555
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		otm2595
orthoMCL	1	0.900	-	-		OOG6_101482
Panther	1	1.100	-	-	O	PTHR10015
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.780