Protein Alignment Hsf and Hsf5

DIOPT Version :9

• Sequence 1: NP_001036555.1
• Gene: Hsf / 37068
• FlyBaseID: FBgn0001222
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: XP_038943302.1
• Gene: Hsf5 / 688111
• RGDID: 1592448
• Length: 624
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 123/592 - (20%)
• Similarity: 194/592 - (32%)
• Gaps: 189/592 - (31%)

  Fly    49 FLAKLWRLVDDADTNRLICWTKDGQSFVIQNQAQFAKELL------------------------- 88
            |.||||||| ::...|.|.|...|:..:| :|..|..|||
  Rat    15 FPAKLWRLV-NSPRYRSIRWDGRGEGLLI-DQPLFEAELLSPPGPGAGGAGGAGSSGGGGGSGVG 77

  Fly    89 -----PLNYKHNNMASFIRQLNMYGFHKIT-----------SIDNGGLRFDRDEIEFSHPFFKRN 137
                 |..:|..|..|||||||:|||.|:.           ....||...|.....|..|.|:|:
  Rat    78 AAGAEPELFKTTNFTSFIRQLNLYGFRKVVLGGPGAAGPGPGPGAGGPAGDGPLHHFHSPHFRRD 142

  Fly   138 SPFLLDQIKRKISNNK----NGDDKGVLKPEAMSKIL-TDVKVMRG------------------- 178
            .|.||..:||..|.||    .|.:.....|....::| |.......
  Rat   143 QPQLLVHLKRLTSANKAKLAAGLEVPCRPPNRFQRLLITSASASASASTSPLQHQDPPPQPAGPR 207

  Fly   179 ----------------RQDNLD--SRFSAMKQENEVL--------------WREIASLRQKHAKQ 211
                            |:|||.  |..|.....:...              |:....:   |..|
  Rat   208 PEQHGPVAVGQFHRSFRRDNLSPYSYVSTSSHNHSTFPLKGLDRTPIPPRTWQNSLGM---HPGQ 269

  Fly   212 QQ----IVNKLIQFLIT---------IVQPSRNMSGVKRHVQLMI-------NNTPEIDRARTTS 256
            .:    ..:|.:.|.:.         .:|||.....|::..|.|:       |.||....::...
  Rat   270 VETSPTFSDKGVPFPVLQRFPTEVTYTLQPSATSVHVQQGPQTMVSSSQKYSNYTPSAQYSQAYY 334

  Fly   257 ETESESGGGPVIHELREELLDEVMNPSPAGYTAASHYDQESVSPP-----AVERPRSNMSISSHN 316
            .|.......|..|   .:.|...:.|:.:.|...:::.    :||     .||...||...|:.:
  Rat   335 PTAVLQCCSPSTH---MDALSSCVTPTASSYAHCNYFQ----NPPMQSSYPVEFLPSNWPCSATD 392

  Fly   317 ---------------VDYSNQS----------VEDLLLQGNGTAGGNILV-GGAASPMAQS-VSQ 354
                           ||..:.|          ||:.........|.:||. ..:::|.:.| .||
  Rat   393 DSKKTEVNLEAVFQIVDELHSSPKLEMVKVEPVENQCPSSQSNRGQHILPNSNSSNPSSTSQASQ 457

  Fly   355 ----SPAQHDVYTVTEAPDSHVQ-EVPNSPPY---------YEEQNVLTTPMVREQEQQKRQQLK 405
                :|...|:.:.....:..:. .:|.||.|         .|...:..:..:::...:.::||.
  Rat   458 LEPLTPVGSDITSFVVGTEQAITCSLPQSPEYIYTIHTAQPLENSTMQESATMQQTHVKLKEQLS 522

  Fly   406 ENNKLRRQAGDVILDAGDILVDSSSPKAQRTSIQHSTQPDVMVQP------MIIKSEP-ENSSGL 463
            .|:.   .:..|::..|   :..|:|:.. :||:..|.|...:.|      :|.:..| ..||..
  Rat   523 HNSP---PSSVVLVQEG---LPFSTPQVD-SSIKCQTNPPESILPSEQMGFLISEMGPASKSSKD 580

  Fly   464 MDLMTPA 470
            ..|.|||
  Rat   581 TGLSTPA 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	43/139 (31%)
		Vert_HS_TF	<607..711	CDD:284062
Hsf5	XP_038943302.1	HSF_DNA-bind	15..152	CDD:395358	42/138 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10015
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030