Protein Alignment Hsf and hsf-1

DIOPT Version :9

• Sequence 1: NP_001036555.1
• Gene: Hsf / 37068
• FlyBaseID: FBgn0001222
• Length: 733
• Species: Drosophila melanogaster
• Sequence 2: NP_493031.1
• Gene: hsf-1 / 173078
• WormBaseID: WBGene00002004
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 634
• Identity: 164/634 - (25%)
• Similarity: 258/634 - (40%)
• Gaps: 152/634 - (23%)

  Fly    29 PSRRMHSYGDAAAIG----------------------SG--------VPAFLAKLWRLVDDADTN 63
            |.|:.|..|   |||                      ||        :|.||.|||.:|:|.:..
 Worm    45 PPRQNHQNG---AIGGKKSSVTIQEVPNNAYLETLNKSGNNKVDDDKLPVFLIKLWNIVEDPNLQ 106

  Fly    64 RLICWTKDGQSFVIQNQAQFAKELLPLNYKHNNMASFIRQLNMYGFHKITSIDNGGL---RFDRD 125
            .::.|...|.||.|.:...|.:.:||..:|||||.|.:||||||||.|:|.:..|||   ..|:|
 Worm   107 SIVHWDDSGASFHISDPYLFGRNVLPHFFKHNNMNSMVRQLNMYGFRKMTPLSQGGLTRTESDQD 171

  Fly   126 EIEFSHPFFKRNSPFLLDQIKRKISNNKNGDDKGVLK--PEAMSKILTDVKVMRGRQDNLDSRFS 188
            .:|||||.|.:..|.||.||||| .:.:..:||.|.:  .:.:..::.:::.||.:..|::.:.:
 Worm   172 HLEFSHPCFVQGRPELLSQIKRK-QSARTVEDKQVNEQTQQNLEVVMAEMRAMREKAKNMEDKMN 235

  Fly   189 AMKQENEVLWREIASLRQKHAKQQQIVNKLIQFLITIVQPSRNMSGVKRHVQLMI-----NNT-- 246
            .:.:||..:|.::.|:||:||:|||...||:.||::::||..:....||.| |.|     |.|
 Worm   236 KLTKENRDMWTQMGSMRQQHARQQQYFKKLLHFLVSVMQPGLSKRVAKRGV-LEIDFCAANGTAG 299

  Fly   247 PEIDRARTTSE--------------------------TESESGGGPVIHELREELLDEVMNPSPA 285
            |...|||..||                          |.:|   ||:|.|:.:|     ...||.
 Worm   300 PNSKRARMNSEEGPYKDVCDLLESLQRETQEPFSRRFTNNE---GPLISEVTDE-----FGNSPV 356

  Fly   286 GYTAA------------SHY-------DQESVSPPAVERPRSNMSISSHNVDYSNQSVEDLLLQG 331
            |..:|            |.|       .:|....|.:.:|:|| |..:|.   :|:...|.:..|
 Worm   357 GRGSAQDLFGDTFGAQSSRYSDGGATSSREQSPHPIISQPQSN-SAGAHG---ANEQKPDDMYMG 417

  Fly   332 NGTAGGNILVGGAASPMAQSVSQSPAQHDVYTVTEAPDS------HVQEVPNSPPYYEEQNVLTT 390
            :|......:..|.::........|||.....|.:.||..      ..|:  .:.||   :|. |.
 Worm   418 SGPLTHENIHRGISALKRDYQGASPASGGPSTSSSAPSGAGAGARMAQK--RAAPY---KNA-TR 476

  Fly   391 PMVREQEQQKRQQLKENNKLRRQAGDVILDAGDILVDSSSPKAQRTSIQHSTQPDVMVQPMIIKS 455
            .|.:.|:.              .:|..:.:....:....|....:.|.|: .||...:..:..:.
 Worm   477 QMAQPQQD--------------YSGGFVNNYSGFMPSDPSMIPYQPSHQY-LQPHQKLMAIEDQH 526

  Fly   456 EPENSSGLMDLMTPANDLYSVNFISEDMPTDIFEDALLPDGVEEAAKLDQQQKFGQSTVSSGKFA 520
            .|..|:...: ..|..:|||        ||     ..|....:.....:.|:.|..:..|...|.
 Worm   527 HPTTSTSSTN-ADPHQNLYS--------PT-----LGLSPSFDRQLSQELQEYFTGTDTSLESFR 577

  Fly   521 S-----NFDVPTNSTLLDANQASTSKAAAKAQASEEEGMAVAKYSGAEN 564
            .     |:|...|:..||.::..:....  .|.:.|.....:.|.|||:
 Worm   578 DLVSNHNWDDFGNNVPLDDDEEGSEDPL--RQLALENAPETSNYDGAED 624

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hsf	NP_001036555.1	HSF	45..148	CDD:214654	50/113 (44%)
		Vert_HS_TF	<607..711	CDD:284062
hsf-1	NP_493031.1	HSF	89..194	CDD:214654	49/104 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160165953
Domainoid	1	1.000	103	1.000	Domainoid score	I4270
eggNOG	1	0.900	-	-		E1_COG5169
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1154048at2759
OrthoFinder	1	1.000	-	-		FOG0000255
OrthoInspector	1	1.000	-	-		oto20458
orthoMCL	1	0.900	-	-		OOG6_101482
Panther	1	1.100	-	-	LDO	PTHR10015
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2153
SonicParanoid	1	1.000	-	-		X160
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.780