Protein Alignment Sema5c and sema3fa

DIOPT Version :9

• Sequence 1: NP_611293.3
• Gene: Sema5c / 37066
• FlyBaseID: FBgn0284221
• Length: 1093
• Species: Drosophila melanogaster
• Sequence 2: XP_005166096.1
• Gene: sema3fa / 544658
• ZFINID: ZDB-GENE-050513-1
• Length: 801
• Species: Danio rerio
• Alignment Length: 560
• Identity: 148/560 - (26%)
• Similarity: 234/560 - (41%)
• Gaps: 117/560 - (20%)

  Fly    52 YISYQDLMS--TAKRF-YDPETTWYSEMLFDVARNQVIVGARDTLYRMSFDLEPLER----ASWG 109
            ::|:::|.|  ||..| :...:|.|..:..|...:::.||::|  |.:|.||..:.:    ..|.
Zfish    44 FLSFKELKSTGTAHHFAFLLNSTDYRILRMDEDHDRMYVGSKD--YILSLDLNDINKEPLIIHWP 106

  Fly   110 ATPSEIAMCQAKGQS-ERWCRNYVRVLHSYGENQLYACGTNAFQPSCSW------------RQME 161
            ..|.:...|...|:. ...|.|::|::..:....||.|||.|:.|.|::            .||.
Zfish   107 VAPQKRTECVLSGKDINGECGNFIRLIEPWNRTHLYVCGTGAYNPICTYVDRGQRAQGFLQDQMP 171

  Fly   162 --------------------------NLTVTGVDSGVVKCPFHPQANSTSLLQSNGQLFVGTATD 200
                                      .|....||||..|||:.|:.||.|.| .||||:.|...|
Zfish   172 RAGGRTSRAADPSASPEPYAPKEYIFRLEPGKVDSGKGKCPYDPKLNSVSAL-INGQLYAGVYID 235

  Fly   201 FSGSDVAILRTGVESNKRFLRTKQYNNNWLSGAQFV-------GSFEAGHFVYFLLRESAAEHMS 258
            |.|:|.||.||  ......:||.|||:.||....||       .:.:....:||..||.|:| |.
Zfish   236 FMGTDSAIFRT--LGKHTAMRTDQYNSRWLHDPTFVHAQLIPDSAEKNDDKLYFFFREKASE-MG 297

  Fly   259 CGKVIYSRVARVCKNDVGGGGQLLRDNWTSFLKARLNCSLPGE--YPYYFDEIQGM----TYAES 317
            ...:..||:.|:|.|| .||...|.:.|::||||||.||:.|.  ...:|||::.:    |....
Zfish   298 QTPMAQSRIGRICLND-DGGHCCLVNKWSTFLKARLICSVTGSDGIETHFDELRDVYIQKTQDTK 361

  Fly   318 ESILYATFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEHSDAAW-----------------KT 365
            ..::|..|..|||...|||||.|:::.:...|:|||..:|..:..|                 .|
Zfish   362 NPVIYGVFSVSGSVFKGSAVCVYSMADVRMVFNGPFAHKEGPNYQWVAYQGKIPYPRPGTCPGGT 426

  Fly   366 VNTNQRSQFQCGTSSIGHWLESSRYQLMDEAVQPIGAEPL-YHSKLE-QFGRLALDIINTKTEQV 428
            ...|.:|........|..   ...:..|..||.|:...|| ..:.:: :|..:.:|.:.......
Zfish   427 FTPNMKSTKDYPDEVINF---MRTHPTMFNAVYPVHKRPLVVRTNVDYEFTTITVDQVAAADGNY 488

  Fly   429 HVLFVASSGNHIKKLSVKYDGDGVQTCLVELWQADDTGTSSLL-----------NMAYLKVS--- 479
            .|||:.:....::|:.|              ...||..|..|:           ::..:|:|
Zfish   489 EVLFLGTDRGTVQKVIV--------------LPRDDLQTEELVLEEVEVFRVPTSITTMKISPKR 539

  Fly   480 DSLYLGTDLALTRIPAQHCSRH-VSQSSCLNSMDPYCGWN 518
            ..||:.:.:.:|.:....|..: .:.:.|..:.||||.|:
Zfish   540 QQLYVSSAVGVTHLALHRCDVYGEACADCCLARDPYCAWD 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema5c	NP_611293.3	Sema_5C	65..496	CDD:200526	136/520 (26%)
		PSI	497..546	CDD:279745	7/23 (30%)
		TSP1	556..607	CDD:214559
		TSP1	610..663	CDD:214559
		TSP1	674..725	CDD:214559
		TSP1	802..834	CDD:214559
		TSP1	853..901	CDD:214559
		TSP1	906..953	CDD:214559
sema3fa	XP_005166096.1	Sema_3F	59..558	CDD:200515	136/522 (26%)
		PSI	557..594	CDD:214655	7/23 (30%)
		Ig_Semaphorin_classIII	619..709	CDD:143279
		IG_like	623..698	CDD:214653

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810