Protein Alignment Sema5c and sema6d

DIOPT Version :9

• Sequence 1: NP_611293.3
• Gene: Sema5c / 37066
• FlyBaseID: FBgn0284221
• Length: 1093
• Species: Drosophila melanogaster
• Sequence 2: NP_998164.3
• Gene: sema6d / 406272
• ZFINID: ZDB-GENE-040426-1933
• Length: 898
• Species: Danio rerio
• Alignment Length: 678
• Identity: 181/678 - (26%)
• Similarity: 303/678 - (44%)
• Gaps: 121/678 - (17%)

  Fly     4 LILKLPKMFSQLW----------LLLILSLLTLEGPQPSTGSGYTTKSSVDLLENDSRYISYQDL 58
            ::.:..::..:.|          |..:|.|:|...|.|..    ....||..|::...|.|:|.|
Zfish     1 MVFEAKRLTERTWCCSVIMAMVLLAWLLPLITSATPFPRD----LQPISVVGLDDSYLYPSFQGL 61

  Fly    59 MS---TAKRFYDPETTWYSEMLFDVARNQVIVGARDTLYRMSF-----DLEPLERASWGATPSEI 115
            :|   |.:...|     |..|:  ..::.:.:.|||.::.::.     ::.|.:..:|.:|  ::
Zfish    62 VSSNETERLGLD-----YQRMM--RIQHMLYIAARDHVFVVNLTTAVDEIIPQQILTWRST--DV 117

  Fly   116 AMCQAKGQSERWCRNYVRVLHSYGENQLYACGTNAFQPSCSWRQMENLTVTGVD-SGVVKCPFHP 179
            :.|..:|::...|.||::||....:..|:||||||..|:|...::.:|...|.: .|..:|||..
Zfish   118 SKCTVRGRNSDECYNYIKVLVPRNDETLFACGTNALNPACRNYRLSSLEQVGQELLGQARCPFES 182

  Fly   180 QANSTSLLQSNGQLFVGTATDFSGSDVAILRTGVESNKRFLRTKQYNNNWLSGAQFVGSFEAGHF 244
            :.::..:. :.|..:..|.|||..||..|.|:.....:..|||.:|::.||....|:.:.|.|::
Zfish   183 RQSNVGVF-AGGHFYSATVTDFQASDAVIYRSLGGEGRPVLRTVKYDSKWLREPHFLHAVEYGNY 246

  Fly   245 VYFLLRESAAEHMSCGKVIYSRVARVCKNDVGGGGQLLRDNWTSFLKARLNCSLPGEYPYYFDEI 309
            |||...|.|.||.:.|||:|||||||||||.||..::|..:||||||||||||:||:..:|||.:
Zfish   247 VYFFFSEIAVEHTAAGKVVYSRVARVCKNDNGGSTRVLDRHWTSFLKARLNCSVPGDTFFYFDVL 311

  Fly   310 QGMT---YAESESILYATFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEHSDAAWKTVNTNQ- 370
            |.:|   .......:...|.|..:||.|||||.:.|..|...|:|.||:|::||:.|..|...|
Zfish   312 QSLTNVLQINQRPAVVGVFTTQTNSIPGSAVCGFYLDDIERVFNGRFKEQKNSDSMWTAVPEEQV 376

  Fly   371 ---RSQFQCGTSSIGHWLESSRY-----------QLMDEAVQPIGAEPLYHSKLEQFGRLALDII 421
               |.....|..|...:..|.::           .||:|:|..:.::||..:....: :|...::
Zfish   377 PKPRPGSCAGEGSASSYSSSVQFPDSVLSFIKTHPLMEESVPSVNSQPLITNTASSY-KLTQIVV 440

  Fly   422 NTKT---EQVHVLFVASSGNHIKKLSVKYDGDGVQTCLVELWQADD-------TGTSSLLNMAYL 476
            :|..   :...|:|:.|....:.|:......:...|.  :|.:..|       .|..::|.:...
Zfish   441 DTAAGPHKNRTVVFLGSEDGRVLKILTNTHTNSSHTS--QLLEDIDVFNPTRCVGERAVLGLELD 503

  Fly   477 KVSDSLYLGTDLALTRIPAQHCSRHVS-QSSCLNSMDPYCGW----------------------- 517
            |...:|::.....:.|:|...|::|.: :..||.:.||||.|
Zfish   504 KEHHALFVAFSSCVIRVPLSRCAQHATCRRRCLYTHDPYCIWLRTGRCADMAPGFKAGFEQDIDG 568

  Fly   518 --NELVERC--------------------MPQPQDSSVLQHWHQAPQITCPVLNAPIDGGWSTWS 560
              ..|.:.|                    :.|..|:..|...:....:...||.|.:.|..:  |
Zfish   569 EQTHLFDTCTDVMSSAGSDVKSAVDSASGVKQLPDADSLSDGYHFTLLGACVLLAFVLGAIA--S 631

  Fly   561 PWAVCQQHEQPDSNCQCRQRSCNNPQPQ 588
            ...|         :|.|||.|.:.|:|:
Zfish   632 GLLV---------SCYCRQSSPSTPEPE 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema5c	NP_611293.3	Sema_5C	65..496	CDD:200526	138/464 (30%)
		PSI	497..546	CDD:279745	14/94 (15%)
		TSP1	556..607	CDD:214559	9/33 (27%)
		TSP1	610..663	CDD:214559
		TSP1	674..725	CDD:214559
		TSP1	802..834	CDD:214559
		TSP1	853..901	CDD:214559
		TSP1	906..953	CDD:214559
sema6d	NP_998164.3	Sema	64..523	CDD:301699	139/471 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810