Protein Alignment Sema5c and Sema6a

DIOPT Version :9

• Sequence 1: NP_611293.3
• Gene: Sema5c / 37066
• FlyBaseID: FBgn0284221
• Length: 1093
• Species: Drosophila melanogaster
• Sequence 2: XP_006525789.1
• Gene: Sema6a / 20358
• MGIID: 1203727
• Length: 1048
• Species: Mus musculus
• Alignment Length: 547
• Identity: 164/547 - (29%)
• Similarity: 268/547 - (48%)
• Gaps: 63/547 - (11%)

  Fly    17 LLLILSLLTLEG---PQPS-----TGSGYTTKSSVDLLENDSRYISYQDLMSTAKRFYDPETTWY 73
            |||.|:||...|   |:.|     :...||.:..|        ::.::...:|.:|..      .
Mouse     6 LLLCLTLLHCAGAGFPEDSEPISISHGNYTKQYPV--------FVGHKPGRNTTQRHR------L 56

  Fly    74 SEMLFDVARNQVIVGARDTLYRMSFDLEPLE------RASWGATPSEIAMCQAKGQSERWCRNYV 132
            ...:..:....:.|.|||.:|.:..|....|      :.:|.:..:::..|:.||:.:..|.|::
Mouse    57 DIQMIMIMNRTLYVAARDHIYTVDIDTSHTEEIYCSKKLTWKSRQADVDTCRMKGKHKDECHNFI 121

  Fly   133 RVLHSYGENQLYACGTNAFQPSCSWRQMENLTVTGVD-SGVVKCPFHPQANSTSLLQSNGQLFVG 196
            :||....::.|:.||||||.|||...:::.|...|.: ||:.:||:..:..:.:|. ::|:|:..
Mouse   122 KVLLKKNDDTLFVCGTNAFNPSCRNYRVDTLETFGDEFSGMARCPYDAKHANIALF-ADGKLYSA 185

  Fly   197 TATDFSGSDVAILRTGVESNKRFLRTKQYNNNWLSGAQFVGSFEAGHFVYFLLRESAAEHMSCGK 261
            |.|||...|..|.|:..:|..  |||.::::.||....||.:.:.|.::||..||.|.|:.:.||
Mouse   186 TVTDFLAIDAVIYRSLGDSPT--LRTVKHDSKWLKEPYFVQAVDYGDYIYFFFREIAVEYNTMGK 248

  Fly   262 VIYSRVARVCKNDVGGGGQLLRDNWTSFLKARLNCSLPGEYPYYFDEIQGMT---YAESESILYA 323
            |::.|||:|||||:||..::|...||||||||||||:||:..:||:.:|.:|   ......::.|
Mouse   249 VVFPRVAQVCKNDMGGSQRVLEKQWTSFLKARLNCSVPGDSHFYFNILQAVTDVIRINGRDVVLA 313

  Fly   324 TFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEHSDAAWKTVNTNQ----RSQFQCGTSSIGHW 384
            ||.|..:||.|||||||::..|...|.|.||:|:..|:.|..|...:    |.....|:||:..:
Mouse   314 TFSTPYNSIPGSAVCAYDMLDIANVFTGRFKEQKSPDSTWTPVPDERVPKPRPGCCAGSSSLEKY 378

  Fly   385 LESSRY-----------QLMDEAVQPIGAEPLYHSKLEQF--GRLALDIINTKTEQVHVLFVASS 436
            ..|:.:           .||||||..|...|.:...:.::  .::|:|......:...|:|:.|.
Mouse   379 ATSNEFPDDTLNFIKTHPLMDEAVPSIINRPWFLRTMVRYRLTKIAVDNAAGPYQNHTVVFLGSE 443

  Fly   437 GNHIKKLSVKYDGDG----------VQTCLVELWQADDTGTSSLLNMAYLKVSDSLYLGTDLALT 491
            ...|.|...:....|          :.....|....|......::.|...:.|.|||:.....:.
Mouse   444 KGIILKFLARIGSSGFLNGSLFLEEMNVYNPEKCSYDGVEDKRIMGMQLDRASGSLYVAFSTCVI 508

  Fly   492 RIPAQHCSRH-VSQSSCLNSMDPYCGW 517
            ::|...|.|| ..:.:|:.|.||||||
Mouse   509 KVPLGRCERHGKCKKTCIASRDPYCGW 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema5c	NP_611293.3	Sema_5C	65..496	CDD:200526	139/467 (30%)
		PSI	497..546	CDD:279745	11/22 (50%)
		TSP1	556..607	CDD:214559
		TSP1	610..663	CDD:214559
		TSP1	674..725	CDD:214559
		TSP1	802..834	CDD:214559
		TSP1	853..901	CDD:214559
		TSP1	906..953	CDD:214559
Sema6a	XP_006525789.1	Sema_6A	48..513	CDD:200527	141/473 (30%)
		PSI	514..>546	CDD:366642	11/22 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810