Protein Alignment Sema5c and Sema3c

DIOPT Version :9

• Sequence 1: NP_611293.3
• Gene: Sema5c / 37066
• FlyBaseID: FBgn0284221
• Length: 1093
• Species: Drosophila melanogaster
• Sequence 2: NP_038685.3
• Gene: Sema3c / 20348
• MGIID: 107557
• Length: 751
• Species: Mus musculus
• Alignment Length: 527
• Identity: 145/527 - (27%)
• Similarity: 258/527 - (48%)
• Gaps: 81/527 - (15%)

  Fly    52 YISYQDLMSTAKRFY---DPETTWYSEMLFDVARNQVIVGARDTLYRMSFD---LEPLERASWGA 110
            |:::.:|..|....|   ..:...|..:|.|..::::.||::|.:..::.:   .|||. ..|.|
Mouse    30 YLTFDELRETKTSEYFSLSHQQLDYRILLMDEDQDRIYVGSKDHILSLNINNISQEPLS-VFWPA 93

  Fly   111 TPSEIAMCQAKGQS-ERWCRNYVRVLHSYGENQLYACGTNAFQPSCSW----RQMEN---LTVTG 167
            :..::..|:..|:. ...|.|:|||:.::....||.||:.||.|.|::    |:.|:   :..:.
Mouse    94 STIKVEECKMAGKDPTHGCGNFVRVIQTFNRTHLYVCGSGAFSPVCTYLNRGRRSEDQVFMIDSK 158

  Fly   168 VDSGVVKCPFHPQANSTSLLQSNGQLFVGTATDFSGSDVAILRTGVESNKRFLRTKQYNNNWLSG 232
            .:||..:|.|:|..|:.|:: .|.:||.|...||.|:|.||.|:..:.|.  :||.|:|:.|||.
Mouse   159 CESGKGRCSFNPNVNTVSVM-INEELFSGMYIDFMGTDAAIFRSLTKRNA--VRTDQHNSKWLSE 220

  Fly   233 AQFV-------GSFEAGHFVYFLLRESAAEHMSCGKVIYSRVARVCKNDVGGGGQLLRDNWTSFL 290
            ..||       |:......|||..:|...::....|.|:|.:||:|.||.||...|: :.||:||
Mouse   221 PMFVDAHVIPDGTDPNDAKVYFFFKERLTDNNRSTKQIHSMIARICPNDTGGQRSLV-NKWTTFL 284

  Fly   291 KARLNCSLPGE--YPYYFDEIQGMTYAESE----SILYATFRTSGSSIFGSAVCAYNLSSINAAF 349
            ||||.||:..|  ...:|||::.:...|::    :::|..|.||.|...|||||.|:||.|...|
Mouse   285 KARLVCSVTDEDGPETHFDELEDVFLLETDNPRTTLVYGIFTTSSSVFKGSAVCVYHLSDIQTVF 349

  Fly   350 DGPFKQQEHSDAAWKTVNTNQRSQF-QCGTSSIGHWLESSR---------------YQLMDEAVQ 398
            :|||..:|..:  .:.::...|..: :.||...|.:..:.|               :.||..::.
Mouse   350 NGPFAHKEGPN--HQLISYQGRIPYPRPGTCPGGAFTPNMRTTKDFPDDVVTFIRNHPLMYNSIY 412

  Fly   399 PIGAEPL-------YHSKLEQFGRLALDIINTKTEQVHVLFVASSGNHIKKLSVKYDGDGVQTCL 456
            ||...||       |     ::.::|:|.:|....:.||||:.:....::|:.|..........|
Mouse   413 PIHRRPLIVRIGTDY-----KYTKIAVDRVNAADGRYHVLFLGTDRGTVQKVVVLPTNSSASGEL 472

  Fly   457 V----ELWQADDTGTSSLLNMAYLKVS---DSLYLGTDLALTRIPAQHCSRHVSQSSCLN---SM 511
            :    |:::       :.:.:..:|:|   ..||:.::..::::....|  |:..::|.:   :.
Mouse   473 ILEELEVFK-------NHVPITTMKISSKKQQLYVSSNEGVSQVSLHRC--HIYGTACADCCLAR 528

  Fly   512 DPYCGWN 518
            ||||.|:
Mouse   529 DPYCAWD 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema5c	NP_611293.3	Sema_5C	65..496	CDD:200526	134/487 (28%)
		PSI	497..546	CDD:279745	8/25 (32%)
		TSP1	556..607	CDD:214559
		TSP1	610..663	CDD:214559
		TSP1	674..725	CDD:214559
		TSP1	802..834	CDD:214559
		TSP1	853..901	CDD:214559
		TSP1	906..953	CDD:214559
Sema3c	NP_038685.3	Sema_3C	45..514	CDD:200512	133/487 (27%)
		PSI	513..550	CDD:214655	8/25 (32%)
		Ig_Semaphorin_classIII	575..664	CDD:143279
		IG_like	579..653	CDD:214653

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3611
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810