Protein Alignment Sema5c and LOC1277222

DIOPT Version :10

• Sequence 1: NP_611293.3
• Gene: Sema5c / 37066
• FlyBaseID: FBgn0284221
• Length: 1093
• Species: Drosophila melanogaster
• Sequence 2: XP_061498911.1
• Gene: LOC1277222 / 1277222
• VectorBaseID: AGAMI1_014366
• Length: 746
• Species: Anopheles gambiae
• Alignment Length: 575
• Identity: 188/575 - (32%)
• Similarity: 294/575 - (51%)
• Gaps: 82/575 - (14%)

  Fly     9 PKMFSQLWLLLILSLLTLEG--------------PQPSTGSGYTTKSSVDLLENDSRYISYQDLM 59
            ||....:.||::..:|.|.|              .||..|.  ||.....|..:......:|
Mosquito    28 PKAALAMVLLVLALVLPLPGAVLGDYENTWNSYYEQPCCGG--TTNGPFHLRHHGDHVREFQ--- 87

  Fly    60 STAKRFYDPETTWYSEMLFDVARNQVIVGARDTLYRM---SFDLEPLERASW--GATPSEIAMCQ 119
              ..:||      |.....|..|:.:.|||.:.:||:   :..:...|:.|.  ..|.::|..|.
Mosquito    88 --CGKFY------YRTFYMDEDRDTLYVGAMNRVYRLNLKNISMTSCEKDSMLLDPTGADIRNCV 144

  Fly   120 AKGQSERW-CRNYVRVLHSYGE-NQLYACGTNAFQPS--CSWRQMENLT----VTGVDSGVVKCP 176
            ::|:||.: |:|::||:..... .:||.|||||..|.  ..:|.:.:|.    |.||..||.|||
Mosquito   145 SRGKSEMFDCKNHIRVIQPMDNGTRLYICGTNAHSPKDVVIFRNLTHLPRSEYVPGVGLGVAKCP 209

  Fly   177 FHPQANSTSLLQSNGQ------LFVGTATDFSGSDVAILRTG---VESNKR---FLRTKQYNNNW 229
            :.|..|||::....|.      |:.||..:|:.:|..|.|..   :.|.|:   |.||.:|::.|
Mosquito   210 YDPIDNSTAIYVHEGNPGGLPALYSGTNAEFTKADTVIFRADLYEMSSGKKMYNFKRTLKYDSKW 274

  Fly   230 LSGAQFVGSFEAGHFVYFLLRESAAEHMSCGKVIYSRVARVCKNDVGGGGQLLRDNWTSFLKARL 294
            |....|||||:.|.:|||..||.|.|:::|||.:|||||||||.|. ||..:|..||.::|||||
Mosquito   275 LDKPNFVGSFDIGEYVYFFFREIAVEYINCGKAVYSRVARVCKKDT-GGKNILNQNWATYLKARL 338

  Fly   295 NCSLPGEYPYYFDEIQGMTYAESESI-LYATFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEH 358
            |||:.||:|:||:|||.:....::.. .||||.||.:.:.|||||:::|..|::||.|.||:|..
Mosquito   339 NCSISGEFPFYFNEIQDVYQMPTDKTKFYATFTTSTNGLVGSAVCSFSLGEIHSAFAGKFKEQAT 403

  Fly   359 SDAAWKTVNTNQRSQFQCGT---------SSIGHWLESSRYQLMDEAVQPIGAEPLYH------S 408
            |::||..|.:::..:.:.||         .::.:::.|  :.|||.||......|:::      :
Mosquito   404 SNSAWLPVMSSKIPEPRPGTCVDDTTTLPDAVLNFIRS--HPLMDRAVTHDYGNPVFYKRDLILT 466

  Fly   409 KLEQFGRLALDIINTKTEQVHVLFVASSGNHIKKLSVKYDGDGVQTC-LVELWQADDTGTSSLLN 472
            || ...::.:||:|   ::..|.::|::...|.|: |:|..||.... |::::  |......:..
Mosquito   467 KL-VVDKITIDILN---QEYLVYYLATNEGRIYKV-VQYFHDGQSRAKLLDIF--DVAPNEPIQV 524

  Fly   473 MAYLKVSDSLYLGTDLALTRIPAQHCSRHVSQSSCLNSM-DPYCGWNELVERCMP 526
            |...:...|||:|||..:.:|....|:|.  ..||...: ||||||:.....|.|
Mosquito   525 MRLSQRYKSLYIGTDSRIKQIDLVMCNRR--YDSCYRCVQDPYCGWDRDSGSCRP 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sema5c	NP_611293.3	Sema_5C	65..496	CDD:200526	162/472 (34%)
		PSI	497..546	CDD:396154	12/31 (39%)
		TSP1	556..607	CDD:214559
		TSP1	610..663	CDD:214559
		TSP1	674..725	CDD:214559
		TSP1	802..834	CDD:214559
		TSP1	853..901	CDD:214559
		TSP1	906..953	CDD:214559
LOC1277222	XP_061498911.1	None