DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sema5c and sema6d

DIOPT Version :10

Sequence 1:NP_611293.3 Gene:Sema5c / 37066 FlyBaseID:FBgn0284221 Length:1093 Species:Drosophila melanogaster
Sequence 2:NP_001120152.1 Gene:sema6d / 100145190 XenbaseID:XB-GENE-967070 Length:1084 Species:Xenopus tropicalis


Alignment Length:485 Identity:152/485 - (31%)
Similarity:248/485 - (51%) Gaps:44/485 - (9%)


- Green bases have known domain annotations that are detailed below.


  Fly    82 RNQVIVGARDTLYRMSF------DLEPLERASWGATPSEIAMCQAKGQSERWCRNYVRVLHSYGE 140
            |:.:.|..||.:|.::.      ::.|..|.:|.:..::...|..||:.:..|.||::|.....:
 Frog    66 RDTLYVAGRDQVYAINLNEVPKTEVTPSRRLTWRSGQADRKNCAMKGKHKDECHNYIKVFVPRND 130

  Fly   141 NQLYACGTNAFQPSCSWRQMENLTVTGVD-SGVVKCPFHPQANSTSLLQSNGQLFVGTATDFSGS 204
            ..::.||||||.|.|.:.::......|.: ||:.:|||..:..:.:|. ::|:|:..|..||..|
 Frog   131 EMVFVCGTNAFNPMCRYYRLNTFDYDGEEISGLARCPFDARQTNVALF-ADGKLYSATMADFQAS 194

  Fly   205 DVAILRTGVESNKRFLRTKQYNNNWLSGAQFVGSFEAGHFVYFLLRESAAEHMSCGKVIYSRVAR 269
            |..|.|:  ..:...|||.:|::.||....|:.:.|.|:::||..||.|.||.:.||.::|||||
 Frog   195 DAVIYRS--MGDGFALRTIKYDSKWLKEPHFLHAIEYGNYIYFFFREIAVEHNNLGKAVHSRVAR 257

  Fly   270 VCKNDVGGGGQLLRDNWTSFLKARLNCSLPGEYPYYFDEIQGMT-YAESESI--LYATFRTSGSS 331
            :||||:||..::|..:||||:|||||||:||:..:|||.:|.:| ..|...|  :...|.|..:|
 Frog   258 ICKNDLGGSQRVLEKHWTSFVKARLNCSVPGDSFFYFDVLQSITDIIEINGIPTVVGVFTTQLNS 322

  Fly   332 IFGSAVCAYNLSSINAAFDGPFKQQEHSDAAWKTVNTNQRSQFQ---CGTSSIGHWLESS----- 388
            |.||||||:.:..|...|.|.||:|:..|:.|..|..::..:.:   |.....|....||     
 Frog   323 IPGSAVCAFTMDDIEKVFRGRFKEQKTPDSVWTAVPEDRVPKPRPGCCARHGYGEGYRSSTEFPD 387

  Fly   389 -------RYQLMDEAVQPIGAEPLYHSKLEQFGRL---ALDIINTKTEQVHVLFVASSGNHIKKL 443
                   .:.|||.|:..|..|| :.:|.....||   |:|.:........|:||.|....:.|:
 Frog   388 ETLSFIKSHPLMDSAIPSIIEEP-WFTKTRVRYRLTAVAVDHLAGPYLNYTVMFVGSEAGVVLKI 451

  Fly   444 SVKYD----GDGVQTCLVELW-QADDTGTS----SLLNMAYLKVSDSLYLGTDLALTRIPAQHCS 499
            ..|.:    .|.|....::.: :|..:|.|    .::::...:...:|::.....:.|:|...|.
 Frog   452 LAKTNPFSLNDSVLLEEIDAYNRAKCSGNSEEDRKVISLQMDRDHHALFVAFSGCIVRLPLSRCE 516

  Fly   500 RHVS-QSSCLNSMDPYCGW--NELVERCMP 526
            |:.| :.||:.:.||||||  :|...|..|
 Frog   517 RYGSCKKSCIGARDPYCGWLNHESCGRVKP 546

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sema5cNP_611293.3 Sema_5C 65..496 CDD:200526 138/450 (31%)
PSI 497..546 CDD:396154 14/33 (42%)
TSP1 556..607 CDD:214559
TSP1 610..663 CDD:214559
TSP1 674..725 CDD:214559
TSP1 802..834 CDD:214559
TSP1 853..901 CDD:214559
TSP1 906..953 CDD:214559
sema6dNP_001120152.1 Sema_6D 49..513 CDD:200530 138/450 (31%)
PSI 514..>543 CDD:396154 12/28 (43%)
ARG80 <829..1080 CDD:227400
Blue background indicates that the domain is not in the aligned region.

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